How does Charles River (CRL) make money?

Charles River (CRL) primarily makes money through Discovery and Safety Assessment, which accounts for 59.8% of total revenue. For TTM through Q4 2025, Charles River generated $4.02B in total revenue with a net profit margin of -3.6%.

What is Charles River (CRL) gross profit margin?

Charles River (CRL) reported a gross profit margin of 32.9% for TTM through Q4 2025, equivalent to $1.32B in gross profit. This means Charles River retains 32.9% of each revenue unit after direct costs of production.

What is Charles River (CRL) operating profit margin?

Charles River (CRL) reported an operating profit margin of 10.7% for TTM through Q4 2025, equivalent to $428.82M in operating profit. This reflects profitability after operating expenses such as R&D, sales, and administration, but before taxes and non-operating items.

What is Charles River (CRL) net profit margin?

Charles River (CRL) reported a net profit margin of -3.6% for TTM through Q4 2025, equivalent to −$144.34M in net profit. This is the share of revenue that remains as profit after all expenses, taxes, and non-operating items.

How much does Charles River (CRL) spend on capital expenditures?

Charles River (CRL) spent $219.15M on capital expenditures in TTM through Q4 2025 (5.5% of total revenue). Capital expenditures represent investments in physical assets such as property, equipment, and infrastructure.

What is Charles River (CRL) free cash flow?

Charles River (CRL) generated $518.49M in free cash flow for TTM through Q4 2025 (12.9% of total revenue). Free cash flow is the cash remaining after capital expenditures and represents the company's ability to fund growth, pay dividends, or reduce debt.

How Charles River (CRL) Makes Money: A Visual Guide

Charles River (CRL) generated $4.02B in revenue but reported a net loss of $144.34M. Its largest revenue source is Discovery and Safety Assessment (59.8% of revenue). Below is an interactive breakdown of how revenue flows through the income statement.

Charles River (CRL) Income Statement Flow — TTM through Q4 2025

Calculated from the four most recent reported quarters, ending December 27, 2025 (reported February 18, 2026).

Frequently asked questions

How does Charles River (CRL) make money?: Charles River (CRL) primarily makes money through Discovery and Safety Assessment, which accounts for 59.8% of total revenue. For TTM through Q4 2025, Charles River generated $4.02B in total revenue with a net profit margin of -3.6%.
What is Charles River (CRL) gross profit margin?: Charles River (CRL) reported a gross profit margin of 32.9% for TTM through Q4 2025, equivalent to $1.32B in gross profit. This means Charles River retains 32.9% of each revenue unit after direct costs of production.
What is Charles River (CRL) operating profit margin?: Charles River (CRL) reported an operating profit margin of 10.7% for TTM through Q4 2025, equivalent to $428.82M in operating profit. This reflects profitability after operating expenses such as R&D, sales, and administration, but before taxes and non-operating items.
What is Charles River (CRL) net profit margin?: Charles River (CRL) reported a net profit margin of -3.6% for TTM through Q4 2025, equivalent to −$144.34M in net profit. This is the share of revenue that remains as profit after all expenses, taxes, and non-operating items.
How much does Charles River (CRL) spend on capital expenditures?: Charles River (CRL) spent $219.15M on capital expenditures in TTM through Q4 2025 (5.5% of total revenue). Capital expenditures represent investments in physical assets such as property, equipment, and infrastructure.
What is Charles River (CRL) free cash flow?: Charles River (CRL) generated $518.49M in free cash flow for TTM through Q4 2025 (12.9% of total revenue). Free cash flow is the cash remaining after capital expenditures and represents the company's ability to fund growth, pay dividends, or reduce debt.

Data & methodology

What is a Sankey diagram?: A Sankey diagram shows how money flows through a company from revenue to net profit. The width of each flow represents its proportion.
How is the data calculated?: We use the income statement from company filings. For TTM (Trailing Twelve Months), we use a pre-aggregated twelve-month view aligned with our latest four quarterly periods. Revenue flows to cost of revenue and gross profit, then to operating expenses (R&D, S&M, G&A) and operating profit.
When was this data last updated?: Based on company filings through TTM through Q4 2025.