Question 1

What is Alto Neuroscience's P/E ratio?

Accepted Answer

Alto Neuroscience (ANRO) P/E ratio is currently not available. When trailing twelve-month earnings are negative (a net loss), the P/E ratio is mathematically meaningless and is reported as not available (N/A). In that case investors typically use P/S, EV/Sales, or forward P/E instead.

Question 2

How is the P/E ratio calculated?

Accepted Answer

P/E = Share Price ÷ Trailing Twelve-Month (TTM) Diluted EPS, or equivalently Market Capitalisation ÷ TTM Net Income. All inputs are sourced from audited GAAP/IFRS filings and translated to USD using period-end exchange rates so the multiple is comparable across companies and currencies.

Question 3

What is the P/E ratio?

Accepted Answer

The price-to-earnings (P/E) ratio, also called the earnings multiple, measures how much investors pay per dollar of a company's trailing twelve-month (TTM) earnings. It is calculated as share price ÷ TTM diluted EPS (equivalent to market capitalisation ÷ TTM net income). A higher P/E implies the market is pricing in stronger future earnings growth or lower risk; a lower P/E can signal slower expected growth, higher risk, or potential undervaluation.

Question 4

What is a good P/E ratio for Alto Neuroscience?

Accepted Answer

There is no universal "good" P/E. As a rule of thumb, the S&P 500 has historically averaged a P/E in the mid-to-high teens; mature, slow-growth businesses commonly trade in the 10–18× range, while high-growth or asset-light companies often trade at 25–50×+. What matters is the comparison to sector peers and to the company's own historical range. For Alto Neuroscience specifically, the relevant sector benchmark is the current sector median of 25.0×.

Question 5

Why does Alto Neuroscience's P/E ratio change over time?

Accepted Answer

Valuation multiples move with two inputs: the numerator (market capitalisation, which tracks the share price) and the denominator (earnings). Share-price changes — driven by interest rates, earnings expectations, risk appetite, and broader market sentiment — typically dominate short-term moves, while changes in the underlying fundamental drive the longer-term trend. As a result, the ratio can rise during stock-price rallies even if the business itself has not become more valuable, and fall during sell-offs even when fundamentals are improving.

Question 6

Why is Alto Neuroscience's P/E ratio not available?

Accepted Answer

When trailing twelve-month earnings are negative (a net loss), the P/E ratio is mathematically meaningless and is reported as not available (N/A). In that case investors typically use P/S, EV/Sales, or forward P/E instead.


2025	$568.24M	−$63.24M	—	—	Dec 31, 2025
2024	$114.15M	−$61.43M	—	—	Dec 31, 2024
2023	$556.50M	−$36.30M	—	—	Dec 31, 2023


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Cigna (CI)	11.1×
Novo Nordisk (NVO)	8.6×
Solventum (SOLV)	7.9×
Universal Health Services (UHS)	7.2×

P/E Ratio for Alto Neuroscience (ANRO)

P/E Ratio daily chart for Alto Neuroscience (ANRO)

Historical P/E Ratio for Alto Neuroscience (ANRO) from 2023 to 2025

About P/E Ratio at Alto Neuroscience (ANRO)

Sector peers by P/E Ratio — chart

Sector peers by P/E Ratio — table

Frequently asked questions

Alto Neuroscience (ANRO) Key Financials

P/E Ratio daily chart for Alto Neuroscience (ANRO)

Historical P/E Ratio for Alto Neuroscience (ANRO) from 2023 to 2025

About P/E Ratio at Alto Neuroscience (ANRO)

Sector peers by P/E Ratio — chart

Sector peers by P/E Ratio — table

Frequently asked questions

+What is Alto Neuroscience's P/E ratio?

+How is the P/E ratio calculated?

+What is the P/E ratio?

+What is a good P/E ratio for Alto Neuroscience?

+Why does Alto Neuroscience's P/E ratio change over time?

+Why is Alto Neuroscience's P/E ratio not available?

Alto Neuroscience (ANRO) Key Financials