Question 1

What is Illumina's P/E ratio?

Accepted Answer

Illumina (ILMN) P/E ratio is 29.3× as of June 5, 2026. The ratio is calculated by dividing market capitalisation by trailing twelve-month earnings (net income), using USD-normalised financials (IAS 21 exchange-rate translation for non-USD reporters).

Question 2

How is the P/E ratio calculated?

Accepted Answer

P/E = Share Price ÷ Trailing Twelve-Month (TTM) Diluted EPS, or equivalently Market Capitalisation ÷ TTM Net Income. All inputs are sourced from audited GAAP/IFRS filings and translated to USD using period-end exchange rates so the multiple is comparable across companies and currencies.

Question 3

What is the P/E ratio?

Accepted Answer

The price-to-earnings (P/E) ratio, also called the earnings multiple, measures how much investors pay per dollar of a company's trailing twelve-month (TTM) earnings. It is calculated as share price ÷ TTM diluted EPS (equivalent to market capitalisation ÷ TTM net income). A higher P/E implies the market is pricing in stronger future earnings growth or lower risk; a lower P/E can signal slower expected growth, higher risk, or potential undervaluation.

Question 4

What is a good P/E ratio for Illumina?

Accepted Answer

There is no universal "good" P/E. As a rule of thumb, the S&P 500 has historically averaged a P/E in the mid-to-high teens; mature, slow-growth businesses commonly trade in the 10–18× range, while high-growth or asset-light companies often trade at 25–50×+. What matters is the comparison to sector peers and to the company's own historical range. For Illumina specifically, the relevant sector benchmark is the current sector median of 25.0×.

Question 5

Is Illumina's P/E ratio high or low?

Accepted Answer

Illumina's P/E ratio of 29.3× is below its own 5-year average of 47.9× and above the sector median of 25.0×. That places the current reading at the 34th percentile of its 10-year history. A higher multiple usually reflects stronger expected growth, lower perceived risk, or higher returns on capital; a lower multiple reflects the opposite.

Question 6

What is Illumina's historical P/E ratio range?

Accepted Answer

In the available daily series, Illumina (ILMN) P/E ratio has ranged from a low of 11.4× in 2025 to a high of 268.6× in 2008. The 5-year average is 47.9× and the 5-year median is 43.1×.

Question 7

What was Illumina's P/E ratio in 2025?

Accepted Answer

Illumina (ILMN) P/E ratio at the end of 2025 was 24.2×. Annual values reflect the multiple on the last trading day of each calendar year, using the trailing twelve-month earnings figure available at that date.

Question 8

Why does Illumina's P/E ratio change over time?

Accepted Answer

Valuation multiples move with two inputs: the numerator (market capitalisation, which tracks the share price) and the denominator (earnings). Share-price changes — driven by interest rates, earnings expectations, risk appetite, and broader market sentiment — typically dominate short-term moves, while changes in the underlying fundamental drive the longer-term trend. As a result, the ratio can rise during stock-price rallies even if the business itself has not become more valuable, and fall during sell-offs even when fundamentals are improving.


2025	$20.58B	$850.00M	24.2×	—	Dec 28, 2025
2024	$21.24B	−$1.22B	—	—	Dec 29, 2024
2023	$21.52B	−$1.16B	—	—	Dec 31, 2023
2022	$31.05B	−$4.40B	—	—	Dec 31, 2022
2021	$58.05B	$761.00M	76.3×	-3.8×	Dec 31, 2021
2020	$52.50B	$656.00M	80.0×	+32.7×	Dec 31, 2020
2019	$47.39B	$1.00B	47.3×	-4.6×	Dec 31, 2019
2018	$42.85B	$826.00M	51.9×	+9.5×	Dec 31, 2018
2017	$31.00B	$732.00M	42.4×	+2.9×	Dec 31, 2017
2016	$18.27B	$462.65M	39.5×	-19.5×	Dec 31, 2016
2015	$27.23B	$461.56M	59.0×	-13.3×	Dec 31, 2015
2014	$25.53B	$353.35M	72.3×	-36.4×	Dec 31, 2014
2013	$13.62B	$125.31M	108.7×	+64.7×	Dec 31, 2013
2012	$6.66B	$151.25M	44.0×	+2.4×	Dec 31, 2012
2011	$3.60B	$86.63M	41.6×	-33.0×	Dec 31, 2011
2010	$9.31B	$124.89M	74.5×	+18.4×	Dec 31, 2010
2009	$4.06B	$72.28M	56.1×	-9.7×	Dec 31, 2009
2008	$3.32B	$50.48M	65.9×	—	Dec 31, 2008
2007	$3.17B	−$278.36M	—	—	Dec 31, 2007
2006	$1.93B	$39.97M	48.4×	—	Dec 31, 2006
2005	$612.39M	−$20.87M	—	—	Dec 31, 2005
2004	$356.46M	−$3.34M	—	—	Dec 31, 2004
2003	$221.24M	−$28.20M	—	—	Dec 31, 2003
2002	$102.66M	−$56.12M	—	—	Dec 31, 2002
2001	$344.59M	−$24.82M	—	—	Dec 31, 2001


Agilent Technologies (A)	23.1×
Medtronic (MDT)	22.2×
McKesson (MCK)	22.2×
ResMed (RMD)	21.6×
GE HealthCare (GEHC)	21.6×
Pfizer (PFE)	21.1×
Quest Diagnostics (DGX)	21.1×
Henry Schein (HSIC)	21.0×
AptarGroup (ATR)	20.9×
IQVIA (IQV)	20.7×
UnitedHealth Group (UNH)	20.4×
Biogen (BIIB)	19.7×
Zoetis (ZTS)	18.9×
Gilead Sciences (GILD)	18.8×
Humana (HUM)	18.5×
Regeneron Pharmaceuticals (REGN)	18.2×
Bristol-Myers Squibb (BMY)	17.0×
HCA Healthcare (HCA)	15.8×
DaVita (DVA)	13.3×
Incyte (INCY)	13.1×
Elevance Health (ELV)	12.3×
Cigna (CI)	11.1×
Novo Nordisk (NVO)	8.6×
Solventum (SOLV)	7.9×
Universal Health Services (UHS)	7.2×

P/E Ratio for Illumina (ILMN)

P/E Ratio daily chart for Illumina (ILMN)

Historical P/E Ratio for Illumina (ILMN) from 2001 to 2025

About P/E Ratio at Illumina (ILMN)

Illumina P/E Ratio by Year

Illumina P/E Ratio 2025: 24.2×

Illumina P/E Ratio 2021: 76.3×

Illumina P/E Ratio 2020: 80.0×

Illumina P/E Ratio 2019: 47.3×

Illumina P/E Ratio 2018: 51.9×

Sector peers by P/E Ratio — chart

Sector peers by P/E Ratio — table

Frequently asked questions

Illumina (ILMN) Key Financials

P/E Ratio daily chart for Illumina (ILMN)

Historical P/E Ratio for Illumina (ILMN) from 2001 to 2025

About P/E Ratio at Illumina (ILMN)

Illumina P/E Ratio by Year

Illumina P/E Ratio 2025: 24.2×

Illumina P/E Ratio 2021: 76.3×

Illumina P/E Ratio 2020: 80.0×

Illumina P/E Ratio 2019: 47.3×

Illumina P/E Ratio 2018: 51.9×

Sector peers by P/E Ratio — chart

Sector peers by P/E Ratio — table

Frequently asked questions

+What is Illumina's P/E ratio?

+How is the P/E ratio calculated?

+What is the P/E ratio?

+What is a good P/E ratio for Illumina?

+Is Illumina's P/E ratio high or low?

+What is Illumina's historical P/E ratio range?

+What was Illumina's P/E ratio in 2025?

+Why does Illumina's P/E ratio change over time?

Illumina (ILMN) Key Financials