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TTM

80.9%

YoY change

−3.85pp

Trough year (2025)

81.8%

Peak year (2018)

97.6%

Gross Margin history chart for Alnylam Pharmaceuticals (ALNY) from 2017 to 2025

Latest: 81.8%

Gross Margin change chart for Alnylam Pharmaceuticals (ALNY) from 2017 to 2025

Latest: −3.85pp

Gross Margin history table for Alnylam Pharmaceuticals (ALNY) from 2017 to 2025

  • 202581.8%-3.85pp
  • 202485.6%+2.59pp
  • 202383.0%-0.71pp
  • 202283.7%+0.33pp
  • 202183.4%-0.76pp
  • 202084.2%-4.43pp
  • 201988.6%-9.00pp
  • 201897.6%+12.46pp
  • 201785.1%

Gross Margin values are taken from Alnylam Pharmaceuticals's reported income statements (quarterly 10-Q and annual 10-K filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the filing date. YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

About Gross Margin at Alnylam Pharmaceuticals (ALNY)

According to Alnylam Pharmaceuticals's latest reported financial statements, the company's latest reported gross margin is 80.9%. Gross margin is gross profit divided by revenue, expressed as a percentage. It shows how much of each sales dollar survives the direct cost of goods sold — before operating expenses, interest, and taxes. A higher gross margin generally signals pricing power and production efficiency. Margins are most meaningful compared against sector peers and a company's own history.

Headline figure above is from the reporting period ending (reported ). Chart and table below cover the full reported history back to .

In 2025, Alnylam Pharmaceuticals (ALNY) gross margin totalled 81.77% – contracted 3.8 percentage points year-over-year.

The highest annual gross margin of 97.59% was reported in 2018. The lowest in the available history was 81.77% in 2025.

Alnylam Pharmaceuticals Gross Margin by Year

Alnylam Pharmaceuticals Gross Margin 2025: 81.8%

Alnylam Pharmaceuticals posted gross margin of 81.77% in 2025, contracted 3.8 percentage points from 2024. This figure represents the lowest annual value in the available history.

Alnylam Pharmaceuticals Gross Margin 2024: 85.6%

In 2024, Alnylam Pharmaceuticals reported gross margin of 85.62%, expanded 2.6 percentage points from 2023.

Alnylam Pharmaceuticals Gross Margin 2023: 83.0%

Alnylam Pharmaceuticals gross margin in 2023 was 83.02%, contracted 0.7 percentage points from 2022.

Alnylam Pharmaceuticals Gross Margin 2022: 83.7%

2022's gross margin for Alnylam Pharmaceuticals came in at 83.73%, expanded 0.3 percentage points from 2021.

Alnylam Pharmaceuticals Gross Margin 2021: 83.4%

Alnylam Pharmaceuticals gross margin in 2021 was 83.40%.

See more financial history for Alnylam Pharmaceuticals (ALNY).

Sector peers by Gross Margin

Healthcare peers of Alnylam Pharmaceuticals (ALNY), ranked by their latest gross margin

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