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Gross Profit for Alnylam Pharmaceuticals (ALNY)

According to Alnylam Pharmaceuticals's latest reported financial statements, the company's current gross profit (TTM) is $3.03B USD. Gross profit equals revenue minus the cost of goods sold (COGS) — what remains from sales after the direct cost of producing the product or service. It does not yet subtract operating expenses, interest, or taxes (see operating income and net income for those steps). Higher gross profit (and gross margin) generally signals pricing power and production efficiency.

Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

TTM (last 4 quarters)

$3.03B

YoY change

+57.8%

5Y CAGR

+48.9%

Peak year (2025)

$3.04B

Cumulative gross profit

$9.53B

Gross Profit history chart for Alnylam Pharmaceuticals (ALNY) from 2002 to 2025

Gross Profit history table for Alnylam Pharmaceuticals (ALNY) from 2002 to 2025

Fiscal yearPeriod endedReportedGross ProfitYoY
2025$3.04B+57.8%
2024$1.92B+26.8%
2023$1.52B+74.8%
2022$868.60M+23.4%
2021$704.14M+69.8%
2020$414.80M+113.1%
2019$194.69M+166.3%
2018$73.11M-4.5%
2017$76.55M+62.3%
2016$47.16M+14.8%
2015$41.10M-18.7%
2014$50.56M+7.2%
2013$47.17M-29.3%
2012$66.72M-19.4%
2011$82.76M-17.3%
2010$100.04M-0.5%
2009$100.53M+4.5%
2008$96.16M+88.9%
2007$50.90M+89.0%
2006$26.93M+371.1%
2005$5.72M+33.6%
2004$4.28M+2330.7%
2003$176,000
2002$0

Gross Profit values are taken from Alnylam Pharmaceuticals's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

Analysis

Alnylam Pharmaceuticals (ALNY) most recent annual gross profit stands at $3.04B (2025) – surged 57.8% year-over-year.

Alnylam Pharmaceuticals gross profit compound annual growth for the 2020–2025 (5 years) window is +48.9%, sustaining 7 straight years of year-over-year growth.

Across the available history, gross profit reached its high of $3.04B in 2025 and its low of $0 in 2002.

Within Healthcare, Alnylam Pharmaceuticals (ALNY) ranks 9th among 8 peers we track. The peer median for gross profit is $53.80B.

Alnylam Pharmaceuticals Gross Profit by Year

Alnylam Pharmaceuticals Gross Profit 2025: $3.04B

Alnylam Pharmaceuticals gross profit in 2025 was $3.04B, surged 57.8% from 2024. This figure represents the highest annual value in the available history.

Alnylam Pharmaceuticals Gross Profit 2024: $1.92B

Alnylam Pharmaceuticals gross profit in 2024 was $1.92B, grew 26.8% from 2023.

Alnylam Pharmaceuticals Gross Profit 2023: $1.52B

Alnylam Pharmaceuticals gross profit in 2023 was $1.52B, surged 74.8% from 2022.

Alnylam Pharmaceuticals Gross Profit 2022: $868.60M

Alnylam Pharmaceuticals gross profit in 2022 was $868.60M, grew 23.4% from 2021.

Alnylam Pharmaceuticals Gross Profit 2021: $704.14M

Alnylam Pharmaceuticals gross profit in 2021 was $704.14M.

See more financial history for Alnylam Pharmaceuticals (ALNY).

Sector peers — Gross Profit

Companies in the same sector as Alnylam Pharmaceuticals, ranked by their latest gross profit.

CompanyGross ProfitSector
Novo Nordisk A/S (NVO)$250.28BHealthcare
UnitedHealth Group Incorporated (UNH)$82.92BHealthcare
Johnson & Johnson (JNJ)$68.56BHealthcare
Eli Lilly and Company (LLY)$54.62BHealthcare
Merck & Co., Inc. (MRK)$52.98BHealthcare
AstraZeneca PLC (AZN)$48.11BHealthcare
AbbVie Inc. (ABBV)$42.96BHealthcare
Amgen Inc. (AMGN)$26.01BHealthcare

Frequently asked questions

What is Alnylam Pharmaceuticals's gross profit?

Latest reported gross profit for Alnylam Pharmaceuticals (ALNY) is $3.03B (period ending December 31, 2025).

How has Alnylam Pharmaceuticals gross profit changed year-over-year?

Alnylam Pharmaceuticals (ALNY) gross profit changed +57.8% year-over-year on the latest annual filing.

What is the long-term growth rate of Alnylam Pharmaceuticals gross profit?

Alnylam Pharmaceuticals (ALNY) gross profit compound annual growth rate is +48.9% over the most recent 5 years available.

When did Alnylam Pharmaceuticals gross profit hit its highest annual value?

Alnylam Pharmaceuticals gross profit reached its highest annual value of $3.04B in 2025.

What was Alnylam Pharmaceuticals gross profit in 2024?

Alnylam Pharmaceuticals (ALNY) gross profit in 2024 was $1.92B.

What was Alnylam Pharmaceuticals gross profit in 2025?

Alnylam Pharmaceuticals (ALNY) gross profit in 2025 was $3.04B.

Metrics overview

Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.