Ticker League

TTM

-144.4%

YoY change

+40.70pp

Trough year (2018)

-3297.2%

Peak year (2009)

1140.9%

Net Profit Margin history chart for Insmed (INSM) from 2002 to 2025

Latest: -210.5%

Net Profit Margin change chart for Insmed (INSM) from 2002 to 2025

Latest: +40.70pp

Net Profit Margin history table for Insmed (INSM) from 2002 to 2025

  • 2025-210.5%+40.70pp
  • 2024-251.2%-5.65pp
  • 2023-245.6%-49.33pp
  • 2022-196.3%+34.38pp
  • 2021-230.6%-51.76pp
  • 2020-178.9%+7.50pp
  • 2019-186.4%+3110.80pp
  • 2018-3297.2%
  • 2014-688.3%-200.75pp
  • 2013-487.6%
  • 2011-1350.8%-1257.82pp
  • 2010-93.0%-1233.91pp
  • 20091140.9%+1274.86pp
  • 2008-133.9%+131.22pp
  • 2007-265.1%
  • 2002-1862.8%

Net Profit Margin values are taken from Insmed's reported income statements (quarterly 10-Q and annual 10-K filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the filing date. YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

About Net Profit Margin at Insmed (INSM)

According to Insmed's latest reported financial statements, the company's latest reported net margin is -144.4%. Net profit margin is net income divided by revenue — the bottom-line share of each sales dollar that remains after all costs, including operating expenses, interest, and taxes. It is the most comprehensive profitability ratio, though it can swing on one-off items, so read it alongside the multi-year trend below.

Headline figure above is from the reporting period ending (reported ). Chart and table below cover the full reported history back to .

In 2025, Insmed (INSM) net margin totalled -210.54% – expanded 40.7 percentage points year-over-year.

The record annual net margin stands at 1140.94%, reached in 2009; the historical low of -3297.17% was recorded in 2018.

Insmed Net Profit Margin by Year

Insmed Net Profit Margin 2025: -210.5%

In 2025, Insmed reported net margin of -210.54%, expanded 40.7 percentage points from 2024.

Insmed Net Profit Margin 2024: -251.2%

Insmed net margin in 2024 was -251.24%, contracted 5.6 percentage points from 2023.

Insmed Net Profit Margin 2023: -245.6%

2023's net margin for Insmed came in at -245.59%, contracted 49.3 percentage points from 2022.

Insmed Net Profit Margin 2022: -196.3%

Insmed posted net margin of -196.26% in 2022, expanded 34.4 percentage points from 2021.

Insmed Net Profit Margin 2021: -230.6%

Insmed net margin in 2021 was -230.63%.

See more financial history for Insmed (INSM).

Sector peers by Net Profit Margin

Healthcare peers of Insmed (INSM), ranked by their latest net margin

Frequently asked questions