Gross Profit for Insmed (INSM)
According to Insmed's latest reported financial statements, the company's current gross profit (TTM) is $481.55M USD. Gross profit equals revenue minus the cost of goods sold (COGS) — what remains from sales after the direct cost of producing the product or service. It does not yet subtract operating expenses, interest, or taxes (see operating income and net income for those steps). Higher gross profit (and gross margin) generally signals pricing power and production efficiency.
Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

INSM
Currently viewingGross ProfitSwitch metric
TTM (last 4 quarters)
$481.55M
YoY change
+73.2%
5Y CAGR
+31.1%
Peak year (2025)
$481.55M
Cumulative gross profit
$1.57B
Gross Profit history chart for Insmed (INSM) from 1999 to 2025
Gross Profit history table for Insmed (INSM) from 1999 to 2025
| Fiscal year | Period ended | Reported | Gross Profit | YoY |
|---|---|---|---|---|
| 2025 | $481.55M | +73.2% | ||
| 2024 | $277.96M | +16.0% | ||
| 2023 | $239.63M | +26.0% | ||
| 2022 | $190.23M | +31.8% | ||
| 2021 | $144.31M | +15.9% | ||
| 2020 | $124.54M | +10.9% | ||
| 2019 | $112.25M | +1414.5% | ||
| 2018 | $7.41M | -355.5% | ||
| 2017 | -$2.90M | +19.0% | ||
| 2016 | -$2.44M | +23.0% | ||
| 2015 | -$1.98M | -91.0% | ||
| 2014 | -$22.04M | — | ||
| 2013 | $0 | -100.0% | ||
| 2012 | -$21.37M | -583.8% | ||
| 2011 | $4.42M | -36.2% | ||
| 2010 | $6.92M | -33.3% | ||
| 2009 | $10.37M | -11.3% | ||
| 2008 | $11.70M | +68.3% | ||
| 2007 | $6.95M | -1493.4% | ||
| 2006 | -$499,000 | — | ||
| 2005 | $0 | — | ||
| 2004 | $0 | — | ||
| 2003 | $0 | — | ||
| 2002 | $0 | — | ||
| 2001 | $0 | — | ||
| 2000 | $0 | -100.0% | ||
| 1999 | $88,000 | — |
Gross Profit values are taken from Insmed's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.
Analysis
The 2025 reading of Insmed (INSM) gross profit is $481.55M – surged 73.2% year-over-year.
Looking at the 2020–2025 (5 years) stretch, Insmed gross profit compounded at +31.1% per year, sustaining 8 straight years of year-over-year growth.
The dataset's maximum gross profit sits at $481.55M (2025); the minimum reading of -$22.04M dates to 2014.
Insmed (INSM) sits 9th of 8 Healthcare peers we track on this metric, against a peer median of $53.80B.
Insmed Gross Profit by Year
Insmed Gross Profit 2025: $481.55M
Insmed gross profit in 2025 was $481.55M, surged 73.2% from 2024. This figure represents the highest annual value in the available history.
Insmed Gross Profit 2024: $277.96M
Insmed gross profit in 2024 was $277.96M, grew 16.0% from 2023.
Insmed Gross Profit 2023: $239.63M
Insmed gross profit in 2023 was $239.63M, grew 26.0% from 2022.
Insmed Gross Profit 2022: $190.23M
Insmed gross profit in 2022 was $190.23M, surged 31.8% from 2021.
Insmed Gross Profit 2021: $144.31M
Insmed gross profit in 2021 was $144.31M.
See more financial history for Insmed (INSM).
Sector peers — Gross Profit
Companies in the same sector as Insmed, ranked by their latest gross profit.
| Company | Gross Profit | Sector |
|---|---|---|
| Novo Nordisk A/S (NVO) | $250.28B | Healthcare |
| UnitedHealth Group Incorporated (UNH) | $82.92B | Healthcare |
| Johnson & Johnson (JNJ) | $68.56B | Healthcare |
| Eli Lilly and Company (LLY) | $54.62B | Healthcare |
| Merck & Co., Inc. (MRK) | $52.98B | Healthcare |
| AstraZeneca PLC (AZN) | $48.11B | Healthcare |
| AbbVie Inc. (ABBV) | $42.96B | Healthcare |
| Amgen Inc. (AMGN) | $26.01B | Healthcare |
Frequently asked questions
What is Insmed's gross profit?
- Latest reported gross profit for Insmed (INSM) is $481.55M (period ending December 31, 2025).
How has Insmed gross profit changed year-over-year?
- Insmed (INSM) gross profit changed +73.2% year-over-year on the latest annual filing.
What is the long-term growth rate of Insmed gross profit?
- Insmed (INSM) gross profit compound annual growth rate is +31.1% over the most recent 5 years available.
When did Insmed gross profit hit its highest annual value?
- Insmed gross profit reached its highest annual value of $481.55M in 2025.
What was Insmed gross profit in 2024?
- Insmed (INSM) gross profit in 2024 was $277.96M.
What was Insmed gross profit in 2025?
- Insmed (INSM) gross profit in 2025 was $481.55M.
Metrics overview
Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.
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