Ticker League

TTM

-137.7%

YoY change

+47.43pp

Trough year (2018)

-3124.9%

Peak year (2009)

-83.6%

Operating Margin history chart for Insmed (INSM) from 2002 to 2025

Latest: -194.0%

Operating Margin change chart for Insmed (INSM) from 2002 to 2025

Latest: +47.43pp

Operating Margin history table for Insmed (INSM) from 2002 to 2025

  • 2025-194.0%+47.43pp
  • 2024-241.5%-8.97pp
  • 2023-232.5%-46.12pp
  • 2022-186.4%+12.64pp
  • 2021-199.0%-37.71pp
  • 2020-161.3%+11.06pp
  • 2019-172.4%+2952.56pp
  • 2018-3124.9%
  • 2014-759.7%-281.30pp
  • 2013-478.4%
  • 2011-1397.3%-1280.39pp
  • 2010-116.9%-33.30pp
  • 2009-83.6%+39.56pp
  • 2008-123.2%+148.29pp
  • 2007-271.5%
  • 2002-1893.8%

Operating Margin values are taken from Insmed's reported income statements (quarterly 10-Q and annual 10-K filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the filing date. YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

About Operating Margin at Insmed (INSM)

According to Insmed's latest reported financial statements, the company's latest reported operating margin is -137.7%. Operating margin is operating income divided by revenue — the share of each sales dollar left after cost of goods sold and operating expenses (SG&A, R&D), but before interest and taxes. It isolates how profitable the core business is before financing and tax decisions, so it is comparable across companies with different capital structures.

Headline figure above is from the reporting period ending (reported ). Chart and table below cover the full reported history back to .

Insmed (INSM) most recent annual operating margin stands at -194.04% (2025) – expanded 47.4 percentage points year-over-year.

2009 marks the peak operating margin at -83.62%, with the historical low of -3124.94% recorded in 2018.

Insmed Operating Margin by Year

Insmed Operating Margin 2025: -194.0%

In 2025, Insmed reported operating margin of -194.04%, expanded 47.4 percentage points from 2024.

Insmed Operating Margin 2024: -241.5%

Insmed operating margin in 2024 was -241.47%, contracted 9.0 percentage points from 2023.

Insmed Operating Margin 2023: -232.5%

2023's operating margin for Insmed came in at -232.51%, contracted 46.1 percentage points from 2022.

Insmed Operating Margin 2022: -186.4%

Insmed posted operating margin of -186.39% in 2022, expanded 12.6 percentage points from 2021.

Insmed Operating Margin 2021: -199.0%

Insmed operating margin in 2021 was -199.03%.

See more financial history for Insmed (INSM).

Sector peers by Operating Margin

Healthcare peers of Insmed (INSM), ranked by their latest operating margin

Frequently asked questions