Operating Income for Insmed (INSM)
According to Insmed's latest reported financial statements, the company's current operating income (TTM) is -$1.18B USD. Operating income is profit from core operations: revenue minus cost of goods sold and operating expenses (SG&A, R&D). It excludes interest, taxes, and non-operating items, so it isolates how profitable the business itself is before financing and tax decisions. Compare with EBITDA and net income.
Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

INSM
Currently viewingOperating IncomeSwitch metric
TTM (last 4 quarters)
-$1.18B
YoY change
+34.0%
5Y CAGR
N/A
Peak year (2010)
-$8.09M
Cumulative operating income
-$5.47B
Operating Income history chart for Insmed (INSM) from 1999 to 2025
Operating Income history table for Insmed (INSM) from 1999 to 2025
| Fiscal year | Period ended | Reported | Operating Income | YoY |
|---|---|---|---|---|
| 2025 | -$1.18B | +34.0% | ||
| 2024 | -$878.25M | +23.8% | ||
| 2023 | -$709.63M | +55.2% | ||
| 2022 | -$457.32M | +21.9% | ||
| 2021 | -$375.09M | +41.4% | ||
| 2020 | -$265.23M | +12.7% | ||
| 2019 | -$235.25M | -23.5% | ||
| 2018 | -$307.34M | +62.7% | ||
| 2017 | -$188.92M | +9.0% | ||
| 2016 | -$173.40M | +47.6% | ||
| 2015 | -$117.49M | +34.5% | ||
| 2014 | -$87.36M | +58.8% | ||
| 2013 | -$55.02M | +29.6% | ||
| 2012 | -$42.44M | -31.2% | ||
| 2011 | -$61.72M | +662.7% | ||
| 2010 | -$8.09M | -6.7% | ||
| 2009 | -$8.67M | -39.8% | ||
| 2008 | -$14.41M | -29.5% | ||
| 2007 | -$20.44M | -62.4% | ||
| 2006 | -$54.37M | +98.2% | ||
| 2005 | -$27.43M | +0.0% | ||
| 2004 | -$27.43M | +159.1% | ||
| 2003 | -$10.59M | -71.4% | ||
| 2002 | -$37.02M | -7.9% | ||
| 2001 | -$40.19M | -50.7% | ||
| 2000 | -$81.53M | +902.9% | ||
| 1999 | -$8.13M | — |
Operating Income values are taken from Insmed's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.
Analysis
Insmed (INSM) most recent annual operating income stands at -$1.18B (2025) – surged 34.0% year-over-year.
-$8.09M stands as the all-time-high annual operating income, posted in 2010, against a low of -$1.18B during 2025.
Among 8 Healthcare peers, Insmed (INSM) ranks 9th; the peer median for operating income is $22.84B.
Insmed Operating Income by Year
Insmed Operating Income 2025: -$1.18B
Insmed operating income in 2025 was -$1.18B, surged 34.0% from 2024. This figure represents the lowest annual value in the available history.
Insmed Operating Income 2024: -$878.25M
Insmed operating income in 2024 was -$878.25M, grew 23.8% from 2023.
Insmed Operating Income 2023: -$709.63M
Insmed operating income in 2023 was -$709.63M, surged 55.2% from 2022.
Insmed Operating Income 2022: -$457.32M
Insmed operating income in 2022 was -$457.32M, grew 21.9% from 2021.
Insmed Operating Income 2021: -$375.09M
Insmed operating income in 2021 was -$375.09M.
See more financial history for Insmed (INSM).
Sector peers — Operating Income
Companies in the same sector as Insmed, ranked by their latest operating income.
| Company | Operating Income | Sector |
|---|---|---|
| Novo Nordisk A/S (NVO) | $127.66B | Healthcare |
| Eli Lilly and Company (LLY) | $29.70B | Healthcare |
| Merck & Co., Inc. (MRK) | $26.78B | Healthcare |
| Johnson & Johnson (JNJ) | $25.60B | Healthcare |
| AbbVie Inc. (ABBV) | $20.09B | Healthcare |
| UnitedHealth Group Incorporated (UNH) | $18.96B | Healthcare |
| AstraZeneca PLC (AZN) | $13.74B | Healthcare |
| Amgen Inc. (AMGN) | $10.68B | Healthcare |
Frequently asked questions
What is Insmed's operating income?
- Latest reported operating income for Insmed (INSM) is -$1.18B (period ending December 31, 2025).
How has Insmed operating income changed year-over-year?
- Insmed (INSM) operating income changed +34.0% year-over-year on the latest annual filing.
When did Insmed operating income hit its highest annual value?
- Insmed operating income reached its highest annual value of -$8.09M in 2010.
What was Insmed operating income in 2024?
- Insmed (INSM) operating income in 2024 was -$878.25M.
What was Insmed operating income in 2025?
- Insmed (INSM) operating income in 2025 was -$1.18B.
Metrics overview
Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.
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