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Operating Income for Insmed (INSM)

According to Insmed's latest reported financial statements, the company's current operating income (TTM) is -$1.18B USD. Operating income is profit from core operations: revenue minus cost of goods sold and operating expenses (SG&A, R&D). It excludes interest, taxes, and non-operating items, so it isolates how profitable the business itself is before financing and tax decisions. Compare with EBITDA and net income.

Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

Insmed Incorporated logo
Insmed

INSM

TTM (last 4 quarters)

-$1.18B

YoY change

+34.0%

5Y CAGR

N/A

Peak year (2010)

-$8.09M

Cumulative operating income

-$5.47B

Operating Income history chart for Insmed (INSM) from 1999 to 2025

Operating Income history table for Insmed (INSM) from 1999 to 2025

Fiscal yearPeriod endedReportedOperating IncomeYoY
2025-$1.18B+34.0%
2024-$878.25M+23.8%
2023-$709.63M+55.2%
2022-$457.32M+21.9%
2021-$375.09M+41.4%
2020-$265.23M+12.7%
2019-$235.25M-23.5%
2018-$307.34M+62.7%
2017-$188.92M+9.0%
2016-$173.40M+47.6%
2015-$117.49M+34.5%
2014-$87.36M+58.8%
2013-$55.02M+29.6%
2012-$42.44M-31.2%
2011-$61.72M+662.7%
2010-$8.09M-6.7%
2009-$8.67M-39.8%
2008-$14.41M-29.5%
2007-$20.44M-62.4%
2006-$54.37M+98.2%
2005-$27.43M+0.0%
2004-$27.43M+159.1%
2003-$10.59M-71.4%
2002-$37.02M-7.9%
2001-$40.19M-50.7%
2000-$81.53M+902.9%
1999-$8.13M

Operating Income values are taken from Insmed's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

Analysis

Insmed (INSM) most recent annual operating income stands at -$1.18B (2025) – surged 34.0% year-over-year.

-$8.09M stands as the all-time-high annual operating income, posted in 2010, against a low of -$1.18B during 2025.

Among 8 Healthcare peers, Insmed (INSM) ranks 9th; the peer median for operating income is $22.84B.

Insmed Operating Income by Year

Insmed Operating Income 2025: -$1.18B

Insmed operating income in 2025 was -$1.18B, surged 34.0% from 2024. This figure represents the lowest annual value in the available history.

Insmed Operating Income 2024: -$878.25M

Insmed operating income in 2024 was -$878.25M, grew 23.8% from 2023.

Insmed Operating Income 2023: -$709.63M

Insmed operating income in 2023 was -$709.63M, surged 55.2% from 2022.

Insmed Operating Income 2022: -$457.32M

Insmed operating income in 2022 was -$457.32M, grew 21.9% from 2021.

Insmed Operating Income 2021: -$375.09M

Insmed operating income in 2021 was -$375.09M.

See more financial history for Insmed (INSM).

Sector peers — Operating Income

Companies in the same sector as Insmed, ranked by their latest operating income.

CompanyOperating IncomeSector
Novo Nordisk A/S (NVO)$127.66BHealthcare
Eli Lilly and Company (LLY)$29.70BHealthcare
Merck & Co., Inc. (MRK)$26.78BHealthcare
Johnson & Johnson (JNJ)$25.60BHealthcare
AbbVie Inc. (ABBV)$20.09BHealthcare
UnitedHealth Group Incorporated (UNH)$18.96BHealthcare
AstraZeneca PLC (AZN)$13.74BHealthcare
Amgen Inc. (AMGN)$10.68BHealthcare

Frequently asked questions

What is Insmed's operating income?

Latest reported operating income for Insmed (INSM) is -$1.18B (period ending December 31, 2025).

How has Insmed operating income changed year-over-year?

Insmed (INSM) operating income changed +34.0% year-over-year on the latest annual filing.

When did Insmed operating income hit its highest annual value?

Insmed operating income reached its highest annual value of -$8.09M in 2010.

What was Insmed operating income in 2024?

Insmed (INSM) operating income in 2024 was -$878.25M.

What was Insmed operating income in 2025?

Insmed (INSM) operating income in 2025 was -$1.18B.

Metrics overview

Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.