TTM
39.0%
YoY change
+41.54pp
Trough year (2009)
-601.1%
Peak year (2022)
48.2%
Latest annual
39.4%
Operating Margin history chart for Vertex Pharmaceuticals (VRTX) from 1990 to 2025
Latest: 39.4%
Operating Margin change chart for Vertex Pharmaceuticals (VRTX) from 1990 to 2025
Latest: +41.54pp
Operating Margin history table for Vertex Pharmaceuticals (VRTX) from 1990 to 2025
| 2025 | 39.4% | +41.54pp | ||
| 2024 | -2.1% | -40.94pp | ||
| 2023 | 38.8% | -9.40pp | ||
| 2022 | 48.2% | +11.50pp | ||
| 2021 | 36.7% | -9.30pp | ||
| 2020 | 46.0% | +17.26pp | ||
| 2019 | 28.8% | +7.93pp | ||
| 2018 | 20.8% | +15.89pp | ||
| 2017 | 5.0% | +4.37pp | ||
| 2016 | 0.6% | +45.98pp | ||
| 2015 | -45.4% | +73.90pp | ||
| 2014 | -119.3% | -44.75pp | ||
| 2013 | -74.5% | -74.70pp | ||
| 2012 | 0.2% | -7.92pp | ||
| 2011 | 8.1% | +493.58pp | ||
| 2010 | -485.5% | +115.58pp | ||
| 2009 | -601.1% | -337.45pp | ||
| 2008 | -263.6% | -52.71pp | ||
| 2007 | -210.9% | -105.08pp | ||
| 2006 | -105.9% | -12.71pp | ||
| 2005 | -93.2% | +57.56pp | ||
| 2004 | -150.7% | +231.88pp | ||
| 2003 | -382.6% | -308.34pp | ||
| 2002 | -74.2% | -19.44pp | ||
| 2001 | -54.8% | -5.30pp | ||
| 2000 | -49.5% | +14.77pp | ||
| 1999 | -64.3% | +8.69pp | ||
| 1998 | -73.0% | -29.14pp | ||
| 1997 | -43.8% | +180.22pp | ||
| 1996 | -224.1% | -104.15pp | ||
| 1995 | -119.9% | -14.30pp | ||
| 1994 | -105.6% | -109.91pp | ||
| 1993 | 4.3% | +267.46pp | ||
| 1992 | -263.2% | -88.16pp | ||
| 1991 | -175.0% | +3.26pp | ||
| 1990 | -178.3% | — |
- 202539.4%+41.54pp
- 2024-2.1%-40.94pp
- 202338.8%-9.40pp
- 202248.2%+11.50pp
- 202136.7%-9.30pp
- 202046.0%+17.26pp
- 201928.8%+7.93pp
- 201820.8%+15.89pp
- 20175.0%+4.37pp
- 20160.6%+45.98pp
- 2015-45.4%+73.90pp
- 2014-119.3%-44.75pp
- 2013-74.5%-74.70pp
- 20120.2%-7.92pp
- 20118.1%+493.58pp
- 2010-485.5%+115.58pp
- 2009-601.1%-337.45pp
- 2008-263.6%-52.71pp
- 2007-210.9%-105.08pp
- 2006-105.9%-12.71pp
- 2005-93.2%+57.56pp
- 2004-150.7%+231.88pp
- 2003-382.6%-308.34pp
- 2002-74.2%-19.44pp
- 2001-54.8%-5.30pp
- 2000-49.5%+14.77pp
- 1999-64.3%+8.69pp
- 1998-73.0%-29.14pp
- 1997-43.8%+180.22pp
- 1996-224.1%-104.15pp
- 1995-119.9%-14.30pp
- 1994-105.6%-109.91pp
- 19934.3%+267.46pp
- 1992-263.2%-88.16pp
- 1991-175.0%+3.26pp
- 1990-178.3%—
Operating Margin values are taken from Vertex Pharmaceuticals's reported income statements (quarterly 10-Q and annual 10-K filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the filing date. YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.
About Operating Margin at Vertex Pharmaceuticals (VRTX)
According to Vertex Pharmaceuticals's latest reported financial statements, the company's latest reported operating margin is 39.0%. Operating margin is operating income divided by revenue — the share of each sales dollar left after cost of goods sold and operating expenses (SG&A, R&D), but before interest and taxes. It isolates how profitable the core business is before financing and tax decisions, so it is comparable across companies with different capital structures.
Headline figure above is from the reporting period ending (reported ). Chart and table below cover the full reported history back to .
As of the 2025 fiscal year, Vertex Pharmaceuticals (VRTX) reported operating margin of 39.43% – expanded 41.5 percentage points year-over-year.
48.23% stands as the all-time-high annual operating margin, posted in 2022, against a low of -601.10% during 2009.
Vertex Pharmaceuticals Operating Margin by Year
Vertex Pharmaceuticals Operating Margin 2025: 39.4%
2025's operating margin for Vertex Pharmaceuticals came in at 39.43%, expanded 41.5 percentage points from 2024.
Vertex Pharmaceuticals Operating Margin 2024: -2.1%
Vertex Pharmaceuticals posted operating margin of -2.11% in 2024, contracted 40.9 percentage points from 2023.
Vertex Pharmaceuticals Operating Margin 2023: 38.8%
In 2023, Vertex Pharmaceuticals reported operating margin of 38.83%, contracted 9.4 percentage points from 2022.
Vertex Pharmaceuticals Operating Margin 2022: 48.2%
Vertex Pharmaceuticals operating margin in 2022 was 48.23%, expanded 11.5 percentage points from 2021. This figure represents the highest annual value in the available history.
Vertex Pharmaceuticals Operating Margin 2021: 36.7%
Vertex Pharmaceuticals operating margin in 2021 was 36.73%.
See more financial history for Vertex Pharmaceuticals (VRTX).
Sector peers by Operating Margin
Healthcare peers of Vertex Pharmaceuticals (VRTX), ranked by their latest operating margin
| 45.9% | |
| 45.3% | |
| 31.6% | |
| 27.6% | |
| 27.6% | |
| 26.4% | |
| 23.7% | |
| 4.2% |
- 45.9%
- 45.3%
- 31.6%
- 27.6%
- 27.6%
- 23.7%
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