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EBITDA for Vertex Pharmaceuticals (VRTX)

According to Vertex Pharmaceuticals's latest reported financial statements, the company's current EBITDA (TTM) is $4.83B USD. EBITDA stands for earnings before interest, taxes, depreciation, and amortization. It is a common proxy for operating cash generation that strips out non-cash charges (depreciation and amortization) and capital structure effects (interest, taxes). Useful for comparing companies with different leverage and asset bases — see operating income and net income for fully GAAP figures.

Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

TTM (last 4 quarters)

$4.83B

YoY change

+921.6%

5Y CAGR

+8.6%

Peak year (2025)

$4.97B

Cumulative EBITDA

$18.52B

EBITDA history chart for Vertex Pharmaceuticals (VRTX) from 1990 to 2025

EBITDA history table for Vertex Pharmaceuticals (VRTX) from 1990 to 2025

Fiscal yearPeriod endedReportedEBITDAYoY
2025$4.97B+921.6%
2024$486.30M-89.4%
2023$4.61B+3.8%
2022$4.44B+52.0%
2021$2.92B-11.2%
2020$3.28B+110.5%
2019$1.56B+120.8%
2018$706.78M+584.5%
2017$103.26M+36.8%
2016$75.46M-118.3%
2015-$411.25M-31.3%
2014-$598.75M+7.9%
2013-$554.75M-1406.4%
2012$42.46M-68.3%
2011$133.94M-119.0%
2010-$704.89M+17.7%
2009-$598.88M+40.5%
2008-$426.19M+10.6%
2007-$385.21M+93.1%
2006-$199.52M+74.3%
2005-$114.45M+6.4%
2004-$107.59M-59.3%
2003-$264.53M+115.0%
2002-$123.05M+26.7%
2001-$97.14M+294.0%
2000-$24.65M-44.4%
1999-$44.30M+2.5%
1998-$43.20M+176.9%
1997-$15.60M-57.0%
1996-$36.30M+59.2%
1995-$22.80M+32.6%
1994-$17.20M-437.3%
1993$5.10M-170.8%
1992-$7.20M+89.5%
1991-$3.80M-7.3%
1990-$4.10M

EBITDA values are taken from Vertex Pharmaceuticals's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

Analysis

As of the 2025 fiscal year, Vertex Pharmaceuticals (VRTX) reported EBITDA of $4.97B – surged 921.6% year-over-year.

Across 2020–2025 (5 years), Vertex Pharmaceuticals EBITDA produced a CAGR of +8.6% – with the latest reading among the more recent periods of the dataset.

The highest annual EBITDA of $4.97B was reported in 2025. The lowest in the available history was -$704.89M in 2010.

Vertex Pharmaceuticals (VRTX) sits 9th of 8 Healthcare peers we track on this metric, against a peer median of $24.21B.

Vertex Pharmaceuticals EBITDA by Year

Vertex Pharmaceuticals EBITDA 2025: $4.97B

Vertex Pharmaceuticals EBITDA in 2025 was $4.97B, surged 921.6% from 2024. This figure represents the highest annual value in the available history.

Vertex Pharmaceuticals EBITDA 2024: $486.30M

Vertex Pharmaceuticals EBITDA in 2024 was $486.30M, plunged 89.4% below 2023.

Vertex Pharmaceuticals EBITDA 2023: $4.61B

Vertex Pharmaceuticals EBITDA in 2023 was $4.61B, edged up 3.8% from 2022.

Vertex Pharmaceuticals EBITDA 2022: $4.44B

Vertex Pharmaceuticals EBITDA in 2022 was $4.44B, surged 52.0% from 2021.

Vertex Pharmaceuticals EBITDA 2021: $2.92B

Vertex Pharmaceuticals EBITDA in 2021 was $2.92B.

See more financial history for Vertex Pharmaceuticals (VRTX).

Sector peers — EBITDA

Companies in the same sector as Vertex Pharmaceuticals, ranked by their latest EBITDA.

CompanyEBITDASector
Novo Nordisk A/S (NVO)$156.73BHealthcare
Johnson & Johnson (JNJ)$41.05BHealthcare
Eli Lilly and Company (LLY)$27.94BHealthcare
Merck & Co., Inc. (MRK)$25.36BHealthcare
UnitedHealth Group Incorporated (UNH)$23.06BHealthcare
AstraZeneca PLC (AZN)$19.83BHealthcare
AbbVie Inc. (ABBV)$17.63BHealthcare
Amgen Inc. (AMGN)$15.84BHealthcare

Frequently asked questions

What is Vertex Pharmaceuticals's EBITDA?

Latest reported EBITDA for Vertex Pharmaceuticals (VRTX) is $4.83B (period ending December 31, 2025).

How has Vertex Pharmaceuticals EBITDA changed year-over-year?

Vertex Pharmaceuticals (VRTX) EBITDA changed +921.6% year-over-year on the latest annual filing.

What is the long-term growth rate of Vertex Pharmaceuticals EBITDA?

Vertex Pharmaceuticals (VRTX) EBITDA compound annual growth rate is +8.6% over the most recent 5 years available.

When did Vertex Pharmaceuticals EBITDA hit its highest annual value?

Vertex Pharmaceuticals EBITDA reached its highest annual value of $4.97B in 2025.

What was Vertex Pharmaceuticals EBITDA in 2024?

Vertex Pharmaceuticals (VRTX) EBITDA in 2024 was $486.30M.

What was Vertex Pharmaceuticals EBITDA in 2025?

Vertex Pharmaceuticals (VRTX) EBITDA in 2025 was $4.97B.

Metrics overview

Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.