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Gross Profit for Vertex Pharmaceuticals (VRTX)

According to Vertex Pharmaceuticals's latest reported financial statements, the company's current gross profit (TTM) is $10.39B USD. Gross profit equals revenue minus the cost of goods sold (COGS) — what remains from sales after the direct cost of producing the product or service. It does not yet subtract operating expenses, interest, or taxes (see operating income and net income for those steps). Higher gross profit (and gross margin) generally signals pricing power and production efficiency.

Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

TTM (last 4 quarters)

$10.39B

YoY change

+8.2%

5Y CAGR

+13.4%

Peak year (2025)

$10.27B

Cumulative gross profit

$65.09B

Gross Profit history chart for Vertex Pharmaceuticals (VRTX) from 1990 to 2025

Gross Profit history table for Vertex Pharmaceuticals (VRTX) from 1990 to 2025

Fiscal yearPeriod endedReportedGross ProfitYoY
2025$10.27B+8.2%
2024$9.49B+10.3%
2023$8.61B+9.6%
2022$7.85B+17.7%
2021$6.67B+22.0%
2020$5.47B+51.3%
2019$3.62B+37.0%
2018$2.64B+19.2%
2017$2.21B+48.4%
2016$1.49B+64.5%
2015$906.79M+74.6%
2014$519.43M-52.0%
2013$1.08B-13.3%
2012$1.25B-6.2%
2011$1.33B+918.2%
2010$130.64M+48.7%
2009$87.85M-45.0%
2008$159.82M-13.7%
2007$185.11M-9.3%
2006$204.19M+35.4%
2005$150.79M+55.3%
2004$97.07M+47.0%
2003$66.02M-50.3%
2002$132.80M+3.9%
2001$127.86M+72.7%
2000$74.05M+13.9%
1999$65.00M+32.9%
1998$48.90M+3.2%
1997$47.40M+187.3%
1996$16.50M-36.0%
1995$25.80M+11.7%
1994$23.10M-27.4%
1993$31.80M+381.8%
1992$6.60M+32.0%
1991$5.00M+117.4%
1990$2.30M

Gross Profit values are taken from Vertex Pharmaceuticals's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

Analysis

As of the 2025 fiscal year, Vertex Pharmaceuticals (VRTX) reported gross profit of $10.27B – grew 8.2% year-over-year.

Vertex Pharmaceuticals gross profit compound annual growth for the 2020–2025 (5 years) window is +13.4%, sustaining 11 straight years of year-over-year growth.

2025 marks the peak gross profit at $10.27B, with the historical low of $2.30M recorded in 1990.

Within Healthcare, Vertex Pharmaceuticals (VRTX) ranks 9th among 8 peers we track. The peer median for gross profit is $53.80B.

Vertex Pharmaceuticals Gross Profit by Year

Vertex Pharmaceuticals Gross Profit 2025: $10.27B

Vertex Pharmaceuticals gross profit in 2025 was $10.27B, grew 8.2% from 2024. This figure represents the highest annual value in the available history.

Vertex Pharmaceuticals Gross Profit 2024: $9.49B

Vertex Pharmaceuticals gross profit in 2024 was $9.49B, grew 10.3% from 2023.

Vertex Pharmaceuticals Gross Profit 2023: $8.61B

Vertex Pharmaceuticals gross profit in 2023 was $8.61B, grew 9.6% from 2022.

Vertex Pharmaceuticals Gross Profit 2022: $7.85B

Vertex Pharmaceuticals gross profit in 2022 was $7.85B, grew 17.7% from 2021.

Vertex Pharmaceuticals Gross Profit 2021: $6.67B

Vertex Pharmaceuticals gross profit in 2021 was $6.67B.

See more financial history for Vertex Pharmaceuticals (VRTX).

Sector peers — Gross Profit

Companies in the same sector as Vertex Pharmaceuticals, ranked by their latest gross profit.

CompanyGross ProfitSector
Novo Nordisk A/S (NVO)$250.28BHealthcare
UnitedHealth Group Incorporated (UNH)$82.92BHealthcare
Johnson & Johnson (JNJ)$68.56BHealthcare
Eli Lilly and Company (LLY)$54.62BHealthcare
Merck & Co., Inc. (MRK)$52.98BHealthcare
AstraZeneca PLC (AZN)$48.11BHealthcare
AbbVie Inc. (ABBV)$42.96BHealthcare
Amgen Inc. (AMGN)$26.01BHealthcare

Frequently asked questions

What is Vertex Pharmaceuticals's gross profit?

Latest reported gross profit for Vertex Pharmaceuticals (VRTX) is $10.39B (period ending December 31, 2025).

How has Vertex Pharmaceuticals gross profit changed year-over-year?

Vertex Pharmaceuticals (VRTX) gross profit changed +8.2% year-over-year on the latest annual filing.

What is the long-term growth rate of Vertex Pharmaceuticals gross profit?

Vertex Pharmaceuticals (VRTX) gross profit compound annual growth rate is +13.4% over the most recent 5 years available.

When did Vertex Pharmaceuticals gross profit hit its highest annual value?

Vertex Pharmaceuticals gross profit reached its highest annual value of $10.27B in 2025.

What was Vertex Pharmaceuticals gross profit in 2024?

Vertex Pharmaceuticals (VRTX) gross profit in 2024 was $9.49B.

What was Vertex Pharmaceuticals gross profit in 2025?

Vertex Pharmaceuticals (VRTX) gross profit in 2025 was $10.27B.

Metrics overview

Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.