Ticker League

TTM

19.4%

YoY change

+47.57pp

Trough year (2000)

-1421.3%

Peak year (2019)

28.3%

Net Profit Margin history chart for Illumina (ILMN) from 2000 to 2025

Latest: 19.6%

Net Profit Margin change chart for Illumina (ILMN) from 2000 to 2025

Latest: +47.57pp

Net Profit Margin history table for Illumina (ILMN) from 2000 to 2025

  • 202519.6%+47.57pp
  • 2024-28.0%-2.20pp
  • 2023-25.8%+70.30pp
  • 2022-96.1%-112.91pp
  • 202116.8%-3.42pp
  • 202020.3%-8.03pp
  • 201928.3%+3.50pp
  • 201824.8%-1.60pp
  • 201726.4%+7.09pp
  • 201619.3%-1.50pp
  • 201520.8%+1.81pp
  • 201419.0%+10.17pp
  • 20138.8%-4.35pp
  • 201213.2%+4.96pp
  • 20118.2%-5.63pp
  • 201013.8%+2.99pp
  • 200910.8%+2.04pp
  • 20088.8%+84.69pp
  • 2007-75.9%-97.54pp
  • 200621.7%+50.05pp
  • 2005-28.4%-16.09pp
  • 2004-12.3%+84.23pp
  • 2003-96.5%+305.17pp
  • 2002-401.7%+596.81pp
  • 2001-998.5%+422.79pp
  • 2000-1421.3%

Net Profit Margin values are taken from Illumina's reported income statements (quarterly 10-Q and annual 10-K filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the filing date. YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

About Net Profit Margin at Illumina (ILMN)

According to Illumina's latest reported financial statements, the company's latest reported net margin is 19.4%. Net profit margin is net income divided by revenue — the bottom-line share of each sales dollar that remains after all costs, including operating expenses, interest, and taxes. It is the most comprehensive profitability ratio, though it can swing on one-off items, so read it alongside the multi-year trend below.

Headline figure above is from the reporting period ending (reported ). Chart and table below cover the full reported history back to .

The 2025 reading of Illumina (ILMN) net margin is 19.59% – expanded 47.6 percentage points year-over-year.

The highest annual net margin of 28.28% was reported in 2019. The lowest in the available history was -1421.31% in 2000.

Illumina Net Profit Margin by Year

Illumina Net Profit Margin 2025: 19.6%

Illumina posted net margin of 19.59% in 2025, expanded 47.6 percentage points from 2024.

Illumina Net Profit Margin 2024: -28.0%

In 2024, Illumina reported net margin of -27.97%, contracted 2.2 percentage points from 2023.

Illumina Net Profit Margin 2023: -25.8%

Illumina net margin in 2023 was -25.78%, expanded 70.3 percentage points from 2022.

Illumina Net Profit Margin 2022: -96.1%

2022's net margin for Illumina came in at -96.07%, contracted 112.9 percentage points from 2021.

Illumina Net Profit Margin 2021: 16.8%

Illumina net margin in 2021 was 16.84%.

See more financial history for Illumina (ILMN).

Sector peers by Net Profit Margin

Healthcare peers of Illumina (ILMN), ranked by their latest net margin

Frequently asked questions