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Operating Income for Illumina (ILMN)

According to Illumina's latest reported financial statements, the company's current operating income (TTM) is $865.00M USD. Operating income is profit from core operations: revenue minus cost of goods sold and operating expenses (SG&A, R&D). It excludes interest, taxes, and non-operating items, so it isolates how profitable the business itself is before financing and tax decisions. Compare with EBITDA and net income.

Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

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TTM (last 4 quarters)

$865.00M

YoY change

-203.8%

5Y CAGR

+8.3%

Peak year (2019)

$985.00M

Cumulative operating income

-$36.57M

Operating Income history chart for Illumina (ILMN) from 1999 to 2025

Operating Income history table for Illumina (ILMN) from 1999 to 2025

Fiscal yearPeriod endedReportedOperating IncomeYoY
2025$865.00M-203.8%
2024-$833.00M-22.1%
2023-$1.07B-74.4%
2022-$4.18B+3297.6%
2021-$123.00M-121.2%
2020$580.00M-41.1%
2019$985.00M+11.6%
2018$883.00M+45.7%
2017$606.00M+3.2%
2016$587.00M-4.2%
2015$613.00M+19.1%
2014$514.71M+283.8%
2013$134.11M-33.2%
2012$200.75M+0.6%
2011$199.46M-5.8%
2010$211.65M+68.5%
2009$125.60M+56.1%
2008$80.46M-126.7%
2007-$301.21M-896.6%
2006$37.81M-276.3%
2005-$21.45M+289.0%
2004-$5.51M-79.3%
2003-$26.62M-36.4%
2002-$41.85M+38.0%
2001-$30.32M+30.5%
2000-$23.23M+292.6%
1999-$5.92M

Operating Income values are taken from Illumina's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

Analysis

As of the 2025 fiscal year, Illumina (ILMN) reported operating income of $865.00M – plunged 203.8% year-over-year.

Illumina operating income compound annual growth for the 2020–2025 (5 years) window is +8.3%, sustaining 3 straight years of year-over-year growth.

Illumina operating income declined from $985.00M in 2019 to $865.00M in 2025, a 12.2% drawdown.

Across the available history, operating income reached its high of $985.00M in 2019 and its low of -$4.18B in 2022.

Among 8 Healthcare peers, Illumina (ILMN) ranks 9th; the peer median for operating income is $22.84B.

Illumina Operating Income by Year

Illumina Operating Income 2025: $865.00M

Illumina operating income in 2025 was $865.00M, plunged 203.8% below 2024.

Illumina Operating Income 2024: -$833.00M

Illumina operating income in 2024 was -$833.00M, declined 22.1% below 2023.

Illumina Operating Income 2023: -$1.07B

Illumina operating income in 2023 was -$1.07B, plunged 74.4% below 2022.

Illumina Operating Income 2022: -$4.18B

Illumina operating income in 2022 was -$4.18B, surged 3297.6% from 2021. This figure represents the lowest annual value in the available history.

Illumina Operating Income 2021: -$123.00M

Illumina operating income in 2021 was -$123.00M.

See more financial history for Illumina (ILMN).

Sector peers — Operating Income

Companies in the same sector as Illumina, ranked by their latest operating income.

CompanyOperating IncomeSector
Novo Nordisk A/S (NVO)$127.66BHealthcare
Eli Lilly and Company (LLY)$29.70BHealthcare
Merck & Co., Inc. (MRK)$26.78BHealthcare
Johnson & Johnson (JNJ)$25.60BHealthcare
AbbVie Inc. (ABBV)$20.09BHealthcare
UnitedHealth Group Incorporated (UNH)$18.96BHealthcare
AstraZeneca PLC (AZN)$13.74BHealthcare
Amgen Inc. (AMGN)$10.68BHealthcare

Frequently asked questions

What is Illumina's operating income?

Latest reported operating income for Illumina (ILMN) is $865.00M (period ending December 28, 2025).

How has Illumina operating income changed year-over-year?

Illumina (ILMN) operating income changed -203.8% year-over-year on the latest annual filing.

What is the long-term growth rate of Illumina operating income?

Illumina (ILMN) operating income compound annual growth rate is +8.3% over the most recent 5 years available.

When did Illumina operating income hit its highest annual value?

Illumina operating income reached its highest annual value of $985.00M in 2019.

What was Illumina operating income in 2024?

Illumina (ILMN) operating income in 2024 was -$833.00M.

What was Illumina operating income in 2025?

Illumina (ILMN) operating income in 2025 was $865.00M.

Metrics overview

Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.