Operating Income for Illumina (ILMN)
According to Illumina's latest reported financial statements, the company's current operating income (TTM) is $865.00M USD. Operating income is profit from core operations: revenue minus cost of goods sold and operating expenses (SG&A, R&D). It excludes interest, taxes, and non-operating items, so it isolates how profitable the business itself is before financing and tax decisions. Compare with EBITDA and net income.
Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

ILMN
Currently viewingRevenueSwitch metric
TTM (last 4 quarters)
$865.00M
YoY change
-203.8%
5Y CAGR
+8.3%
Peak year (2019)
$985.00M
Cumulative operating income
-$36.57M
Operating Income history chart for Illumina (ILMN) from 1999 to 2025
Operating Income history table for Illumina (ILMN) from 1999 to 2025
| Fiscal year | Period ended | Reported | Operating Income | YoY |
|---|---|---|---|---|
| 2025 | $865.00M | -203.8% | ||
| 2024 | -$833.00M | -22.1% | ||
| 2023 | -$1.07B | -74.4% | ||
| 2022 | -$4.18B | +3297.6% | ||
| 2021 | -$123.00M | -121.2% | ||
| 2020 | $580.00M | -41.1% | ||
| 2019 | $985.00M | +11.6% | ||
| 2018 | $883.00M | +45.7% | ||
| 2017 | $606.00M | +3.2% | ||
| 2016 | $587.00M | -4.2% | ||
| 2015 | $613.00M | +19.1% | ||
| 2014 | $514.71M | +283.8% | ||
| 2013 | $134.11M | -33.2% | ||
| 2012 | $200.75M | +0.6% | ||
| 2011 | $199.46M | -5.8% | ||
| 2010 | $211.65M | +68.5% | ||
| 2009 | $125.60M | +56.1% | ||
| 2008 | $80.46M | -126.7% | ||
| 2007 | -$301.21M | -896.6% | ||
| 2006 | $37.81M | -276.3% | ||
| 2005 | -$21.45M | +289.0% | ||
| 2004 | -$5.51M | -79.3% | ||
| 2003 | -$26.62M | -36.4% | ||
| 2002 | -$41.85M | +38.0% | ||
| 2001 | -$30.32M | +30.5% | ||
| 2000 | -$23.23M | +292.6% | ||
| 1999 | -$5.92M | — |
Operating Income values are taken from Illumina's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.
Analysis
As of the 2025 fiscal year, Illumina (ILMN) reported operating income of $865.00M – plunged 203.8% year-over-year.
Illumina operating income compound annual growth for the 2020–2025 (5 years) window is +8.3%, sustaining 3 straight years of year-over-year growth.
Illumina operating income declined from $985.00M in 2019 to $865.00M in 2025, a 12.2% drawdown.
Across the available history, operating income reached its high of $985.00M in 2019 and its low of -$4.18B in 2022.
Among 8 Healthcare peers, Illumina (ILMN) ranks 9th; the peer median for operating income is $22.84B.
Illumina Operating Income by Year
Illumina Operating Income 2025: $865.00M
Illumina operating income in 2025 was $865.00M, plunged 203.8% below 2024.
Illumina Operating Income 2024: -$833.00M
Illumina operating income in 2024 was -$833.00M, declined 22.1% below 2023.
Illumina Operating Income 2023: -$1.07B
Illumina operating income in 2023 was -$1.07B, plunged 74.4% below 2022.
Illumina Operating Income 2022: -$4.18B
Illumina operating income in 2022 was -$4.18B, surged 3297.6% from 2021. This figure represents the lowest annual value in the available history.
Illumina Operating Income 2021: -$123.00M
Illumina operating income in 2021 was -$123.00M.
See more financial history for Illumina (ILMN).
Sector peers — Operating Income
Companies in the same sector as Illumina, ranked by their latest operating income.
| Company | Operating Income | Sector |
|---|---|---|
| Novo Nordisk A/S (NVO) | $127.66B | Healthcare |
| Eli Lilly and Company (LLY) | $29.70B | Healthcare |
| Merck & Co., Inc. (MRK) | $26.78B | Healthcare |
| Johnson & Johnson (JNJ) | $25.60B | Healthcare |
| AbbVie Inc. (ABBV) | $20.09B | Healthcare |
| UnitedHealth Group Incorporated (UNH) | $18.96B | Healthcare |
| AstraZeneca PLC (AZN) | $13.74B | Healthcare |
| Amgen Inc. (AMGN) | $10.68B | Healthcare |
Frequently asked questions
What is Illumina's operating income?
- Latest reported operating income for Illumina (ILMN) is $865.00M (period ending December 28, 2025).
How has Illumina operating income changed year-over-year?
- Illumina (ILMN) operating income changed -203.8% year-over-year on the latest annual filing.
What is the long-term growth rate of Illumina operating income?
- Illumina (ILMN) operating income compound annual growth rate is +8.3% over the most recent 5 years available.
When did Illumina operating income hit its highest annual value?
- Illumina operating income reached its highest annual value of $985.00M in 2019.
What was Illumina operating income in 2024?
- Illumina (ILMN) operating income in 2024 was -$833.00M.
What was Illumina operating income in 2025?
- Illumina (ILMN) operating income in 2025 was $865.00M.
Metrics overview
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