Ticker League

TTM

21.5%

YoY change

+38.97pp

Trough year (2000)

-1774.9%

Peak year (2019)

27.8%

Operating Margin history chart for Illumina (ILMN) from 2000 to 2025

Latest: 19.9%

Operating Margin change chart for Illumina (ILMN) from 2000 to 2025

Latest: +38.97pp

Operating Margin history table for Illumina (ILMN) from 2000 to 2025

  • 202519.9%+38.97pp
  • 2024-19.1%+4.68pp
  • 2023-23.7%+67.43pp
  • 2022-91.2%-88.45pp
  • 2021-2.7%-20.62pp
  • 202017.9%-9.89pp
  • 201927.8%+1.31pp
  • 201826.5%+4.47pp
  • 201722.0%-2.45pp
  • 201624.5%-3.14pp
  • 201527.6%-0.04pp
  • 201427.7%+18.22pp
  • 20139.4%-8.04pp
  • 201217.5%-1.42pp
  • 201118.9%-4.55pp
  • 201023.4%+4.60pp
  • 200918.8%+4.81pp
  • 200814.0%+96.15pp
  • 2007-82.1%-102.60pp
  • 200620.5%+49.66pp
  • 2005-29.2%-18.28pp
  • 2004-10.9%+84.06pp
  • 2003-95.0%+321.92pp
  • 2002-416.9%+802.71pp
  • 2001-1219.6%+555.28pp
  • 2000-1774.9%

Operating Margin values are taken from Illumina's reported income statements (quarterly 10-Q and annual 10-K filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the filing date. YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

About Operating Margin at Illumina (ILMN)

According to Illumina's latest reported financial statements, the company's latest reported operating margin is 21.5%. Operating margin is operating income divided by revenue — the share of each sales dollar left after cost of goods sold and operating expenses (SG&A, R&D), but before interest and taxes. It isolates how profitable the core business is before financing and tax decisions, so it is comparable across companies with different capital structures.

Headline figure above is from the reporting period ending (reported ). Chart and table below cover the full reported history back to .

As of the 2025 fiscal year, Illumina (ILMN) reported operating margin of 19.92% – expanded 39.0 percentage points year-over-year.

The record annual operating margin stands at 27.80%, reached in 2019; the historical low of -1774.87% was recorded in 2000.

Illumina Operating Margin by Year

Illumina Operating Margin 2025: 19.9%

Illumina posted operating margin of 19.92% in 2025, expanded 39.0 percentage points from 2024.

Illumina Operating Margin 2024: -19.1%

In 2024, Illumina reported operating margin of -19.05%, expanded 4.7 percentage points from 2023.

Illumina Operating Margin 2023: -23.7%

Illumina operating margin in 2023 was -23.73%, expanded 67.4 percentage points from 2022.

Illumina Operating Margin 2022: -91.2%

2022's operating margin for Illumina came in at -91.16%, contracted 88.4 percentage points from 2021.

Illumina Operating Margin 2021: -2.7%

Illumina operating margin in 2021 was -2.72%.

See more financial history for Illumina (ILMN).

Sector peers by Operating Margin

Healthcare peers of Illumina (ILMN), ranked by their latest operating margin

Frequently asked questions