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Gross Profit for Illumina (ILMN)

According to Illumina's latest reported financial statements, the company's current gross profit (TTM) is $2.89B USD. Gross profit equals revenue minus the cost of goods sold (COGS) — what remains from sales after the direct cost of producing the product or service. It does not yet subtract operating expenses, interest, or taxes (see operating income and net income for those steps). Higher gross profit (and gross margin) generally signals pricing power and production efficiency.

Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

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TTM (last 4 quarters)

$2.89B

YoY change

+0.9%

5Y CAGR

+5.6%

Peak year (2021)

$3.15B

Cumulative gross profit

$32.23B

Gross Profit history chart for Illumina (ILMN) from 1999 to 2025

Gross Profit history table for Illumina (ILMN) from 1999 to 2025

Fiscal yearPeriod endedReportedGross ProfitYoY
2025$2.89B+0.9%
2024$2.86B+4.3%
2023$2.74B-7.7%
2022$2.97B-5.8%
2021$3.15B+43.2%
2020$2.20B-10.7%
2019$2.47B+7.3%
2018$2.30B+26.0%
2017$1.83B+9.6%
2016$1.67B+7.6%
2015$1.55B+19.4%
2014$1.30B+42.3%
2013$911.89M+17.9%
2012$773.53M+9.1%
2011$709.10M+17.9%
2010$601.54M+30.6%
2009$460.56M+25.3%
2008$367.60M+56.9%
2007$234.36M+87.1%
2006$125.24M+148.9%
2005$50.32M+34.8%
2004$37.32M+107.4%
2003$18.00M+176.7%
2002$6.50M+237.2%
2001$1.93M+13.0%
2000$1.71M+199.3%
1999$570,393

Gross Profit values are taken from Illumina's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.

Analysis

As of the 2025 fiscal year, Illumina (ILMN) reported gross profit of $2.89B – edged up 0.9% year-over-year.

Illumina gross profit compound annual growth for the 2020–2025 (5 years) window is +5.6%, sustaining 2 straight years of year-over-year growth.

Illumina gross profit declined from $3.15B in 2021 to $2.89B in 2025, a 8.5% drawdown.

Across the available history, gross profit reached its high of $3.15B in 2021 and its low of $570,393 in 1999.

Among 8 Healthcare peers, Illumina (ILMN) ranks 9th; the peer median for gross profit is $53.80B.

Illumina Gross Profit by Year

Illumina Gross Profit 2025: $2.89B

Illumina gross profit in 2025 was $2.89B, edged up 0.9% from 2024.

Illumina Gross Profit 2024: $2.86B

Illumina gross profit in 2024 was $2.86B, edged up 4.3% from 2023.

Illumina Gross Profit 2023: $2.74B

Illumina gross profit in 2023 was $2.74B, declined 7.7% below 2022.

Illumina Gross Profit 2022: $2.97B

Illumina gross profit in 2022 was $2.97B, declined 5.8% below 2021.

Illumina Gross Profit 2021: $3.15B

Illumina gross profit in 2021 was $3.15B.

See more financial history for Illumina (ILMN).

Sector peers — Gross Profit

Companies in the same sector as Illumina, ranked by their latest gross profit.

CompanyGross ProfitSector
Novo Nordisk A/S (NVO)$250.28BHealthcare
UnitedHealth Group Incorporated (UNH)$82.92BHealthcare
Johnson & Johnson (JNJ)$68.56BHealthcare
Eli Lilly and Company (LLY)$54.62BHealthcare
Merck & Co., Inc. (MRK)$52.98BHealthcare
AstraZeneca PLC (AZN)$48.11BHealthcare
AbbVie Inc. (ABBV)$42.96BHealthcare
Amgen Inc. (AMGN)$26.01BHealthcare

Frequently asked questions

What is Illumina's gross profit?

Latest reported gross profit for Illumina (ILMN) is $2.89B (period ending December 28, 2025).

How has Illumina gross profit changed year-over-year?

Illumina (ILMN) gross profit changed +0.9% year-over-year on the latest annual filing.

What is the long-term growth rate of Illumina gross profit?

Illumina (ILMN) gross profit compound annual growth rate is +5.6% over the most recent 5 years available.

When did Illumina gross profit hit its highest annual value?

Illumina gross profit reached its highest annual value of $3.15B in 2021.

What was Illumina gross profit in 2024?

Illumina (ILMN) gross profit in 2024 was $2.86B.

What was Illumina gross profit in 2025?

Illumina (ILMN) gross profit in 2025 was $2.89B.

Metrics overview

Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.