Gross Profit for Pfizer (PFE)
According to Pfizer's latest reported financial statements, the company's current gross profit (TTM) is $44.01B USD. Gross profit equals revenue minus the cost of goods sold (COGS) — what remains from sales after the direct cost of producing the product or service. It does not yet subtract operating expenses, interest, or taxes (see operating income and net income for those steps). Higher gross profit (and gross margin) generally signals pricing power and production efficiency.
Headline TTM above sums the four reported quarters through (reported ). Chart and table below cover the full reported history back to .

PFE
Currently viewingGross ProfitSwitch metric
TTM (last 4 quarters)
$44.01B
YoY change
+5.2%
5Y CAGR
+8.1%
Peak year (2022)
$62.09B
Cumulative gross profit
$1.08T
Gross Profit history chart for Pfizer (PFE) from 1985 to 2025
Gross Profit history table for Pfizer (PFE) from 1985 to 2025
| Fiscal year | Period ended | Reported | Gross Profit | YoY |
|---|---|---|---|---|
| 2025 | $44.01B | +5.2% | ||
| 2024 | $41.85B | +37.9% | ||
| 2023 | $30.34B | -51.1% | ||
| 2022 | $62.09B | +32.5% | ||
| 2021 | $46.88B | +56.9% | ||
| 2020 | $29.88B | +4.7% | ||
| 2019 | $28.55B | -24.2% | ||
| 2018 | $37.64B | +2.4% | ||
| 2017 | $36.77B | -0.3% | ||
| 2016 | $36.87B | +3.3% | ||
| 2015 | $35.69B | -1.7% | ||
| 2014 | $36.30B | -3.5% | ||
| 2013 | $37.63B | -6.0% | ||
| 2012 | $40.02B | -8.8% | ||
| 2011 | $43.87B | -5.3% | ||
| 2010 | $46.34B | +20.6% | ||
| 2009 | $38.42B | +0.4% | ||
| 2008 | $38.26B | +4.2% | ||
| 2007 | $36.70B | -3.1% | ||
| 2006 | $37.86B | +2.6% | ||
| 2005 | $36.90B | -11.3% | ||
| 2004 | $41.61B | +17.7% | ||
| 2003 | $35.36B | +24.8% | ||
| 2002 | $28.33B | +4.1% | ||
| 2001 | $27.23B | +6.7% | ||
| 2000 | $25.52B | +79.5% | ||
| 1999 | $14.22B | +19.1% | ||
| 1998 | $11.94B | +11.2% | ||
| 1997 | $10.73B | +12.3% | ||
| 1996 | $9.56B | +16.1% | ||
| 1995 | $8.23B | +23.7% | ||
| 1994 | $6.65B | +11.6% | ||
| 1993 | $5.96B | +9.0% | ||
| 1992 | $5.47B | +9.5% | ||
| 1991 | $4.99B | +14.2% | ||
| 1990 | $4.37B | +14.5% | ||
| 1989 | $3.82B | +7.2% | ||
| 1988 | $3.56B | +11.8% | ||
| 1987 | $3.18B | +9.7% | ||
| 1986 | $2.90B | +11.3% | ||
| 1985 | $2.61B | — |
Gross Profit values are taken from Pfizer's reported income statements (10-Q quarterly and 10-K annual filings with the U.S. Securities and Exchange Commission). Each row shows the period end date and the date the filing was reported; YoY compares each figure to the same period one year earlier. Amounts are in USD as filed.
Analysis
In 2025, Pfizer (PFE) gross profit totalled $44.01B – grew 5.2% year-over-year.
Through 2020–2025 (5 years), Pfizer gross profit delivered a +8.1% annualised rate; sustaining 2 straight years of year-over-year growth.
Between 2022 and 2025, Pfizer gross profit declined 29.1%, falling from $62.09B to $44.01B.
Across the available history, gross profit reached its high of $62.09B in 2022 and its low of $2.61B in 1985.
Among 8 Healthcare peers, Pfizer (PFE) ranks 7th; the peer median for gross profit is $53.80B.
Pfizer Gross Profit by Year
Pfizer Gross Profit 2025: $44.01B
Pfizer gross profit in 2025 was $44.01B, grew 5.2% from 2024.
Pfizer Gross Profit 2024: $41.85B
Pfizer gross profit in 2024 was $41.85B, surged 37.9% from 2023.
Pfizer Gross Profit 2023: $30.34B
Pfizer gross profit in 2023 was $30.34B, plunged 51.1% below 2022.
Pfizer Gross Profit 2022: $62.09B
Pfizer gross profit in 2022 was $62.09B, surged 32.5% from 2021. This figure represents the highest annual value in the available history.
Pfizer Gross Profit 2021: $46.88B
Pfizer gross profit in 2021 was $46.88B.
See more financial history for Pfizer (PFE).
Sector peers — Gross Profit
Companies in the same sector as Pfizer, ranked by their latest gross profit.
| Company | Gross Profit | Sector |
|---|---|---|
| Novo Nordisk A/S (NVO) | $250.28B | Healthcare |
| UnitedHealth Group Incorporated (UNH) | $82.92B | Healthcare |
| Johnson & Johnson (JNJ) | $68.56B | Healthcare |
| Eli Lilly and Company (LLY) | $54.62B | Healthcare |
| Merck & Co., Inc. (MRK) | $52.98B | Healthcare |
| AstraZeneca PLC (AZN) | $48.11B | Healthcare |
| AbbVie Inc. (ABBV) | $42.96B | Healthcare |
| Amgen Inc. (AMGN) | $26.01B | Healthcare |
Frequently asked questions
What is Pfizer's gross profit?
- Latest reported gross profit for Pfizer (PFE) is $44.01B (period ending December 31, 2025).
How has Pfizer gross profit changed year-over-year?
- Pfizer (PFE) gross profit changed +5.2% year-over-year on the latest annual filing.
What is the long-term growth rate of Pfizer gross profit?
- Pfizer (PFE) gross profit compound annual growth rate is +8.1% over the most recent 5 years available.
When did Pfizer gross profit hit its highest annual value?
- Pfizer gross profit reached its highest annual value of $62.09B in 2022.
What was Pfizer gross profit in 2024?
- Pfizer (PFE) gross profit in 2024 was $41.85B.
What was Pfizer gross profit in 2025?
- Pfizer (PFE) gross profit in 2025 was $44.01B.
Metrics overview
Pick a metric for charts, filings, and peers — each row shows the latest TTM or annual value with year-over-year change.
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