How does Pfizer (PFE) make money?

Pfizer (PFE) primarily makes money through Biopharma Segment, which accounts for 100% of total revenue. For TTM through Q4 2025, Pfizer generated $62.58B in total revenue with a net profit margin of 12.4%.

What is Pfizer (PFE) gross profit margin?

Pfizer (PFE) reported a gross profit margin of 70.3% for TTM through Q4 2025, equivalent to $44.01B in gross profit. This means Pfizer retains 70.3% of each revenue unit after direct costs of production.

What is Pfizer (PFE) operating profit margin?

Pfizer (PFE) reported an operating profit margin of 24.7% for TTM through Q4 2025, equivalent to $15.44B in operating profit. This reflects profitability after operating expenses such as R&D, sales, and administration, but before taxes and non-operating items.

What is Pfizer (PFE) net profit margin?

Pfizer (PFE) reported a net profit margin of 12.4% for TTM through Q4 2025, equivalent to $7.77B in net profit. This is the share of revenue that remains as profit after all expenses, taxes, and non-operating items.

How much does Pfizer (PFE) invest in R&D?

Pfizer (PFE) invested $11.98B in research and development in TTM through Q4 2025 (19.1% of total revenue). R&D spending reflects investment in future products, services, and technologies.

How much does Pfizer (PFE) spend on capital expenditures?

Pfizer (PFE) spent $2.63B on capital expenditures in TTM through Q4 2025 (4.2% of total revenue). Capital expenditures represent investments in physical assets such as property, equipment, and infrastructure.

What is Pfizer (PFE) free cash flow?

Pfizer (PFE) generated $9.08B in free cash flow for TTM through Q4 2025 (14.5% of total revenue). Free cash flow is the cash remaining after capital expenditures and represents the company's ability to fund growth, pay dividends, or reduce debt.

How Pfizer (PFE) Makes Money: A Visual Guide

Pfizer (PFE) generated $62.58B in revenue, earning $7.77B in net profit (12.4% margin). Its largest revenue source is Biopharma Segment (100% of revenue). Below is an interactive breakdown of how revenue flows through the income statement.

Pfizer (PFE) Income Statement Flow — TTM through Q4 2025

Calculated from the four most recent reported quarters, ending December 31, 2025 (reported February 26, 2026).

Frequently asked questions

How does Pfizer (PFE) make money?: Pfizer (PFE) primarily makes money through Biopharma Segment, which accounts for 100% of total revenue. For TTM through Q4 2025, Pfizer generated $62.58B in total revenue with a net profit margin of 12.4%.
What is Pfizer (PFE) gross profit margin?: Pfizer (PFE) reported a gross profit margin of 70.3% for TTM through Q4 2025, equivalent to $44.01B in gross profit. This means Pfizer retains 70.3% of each revenue unit after direct costs of production.
What is Pfizer (PFE) operating profit margin?: Pfizer (PFE) reported an operating profit margin of 24.7% for TTM through Q4 2025, equivalent to $15.44B in operating profit. This reflects profitability after operating expenses such as R&D, sales, and administration, but before taxes and non-operating items.
What is Pfizer (PFE) net profit margin?: Pfizer (PFE) reported a net profit margin of 12.4% for TTM through Q4 2025, equivalent to $7.77B in net profit. This is the share of revenue that remains as profit after all expenses, taxes, and non-operating items.
How much does Pfizer (PFE) invest in R&D?: Pfizer (PFE) invested $11.98B in research and development in TTM through Q4 2025 (19.1% of total revenue). R&D spending reflects investment in future products, services, and technologies.
How much does Pfizer (PFE) spend on capital expenditures?: Pfizer (PFE) spent $2.63B on capital expenditures in TTM through Q4 2025 (4.2% of total revenue). Capital expenditures represent investments in physical assets such as property, equipment, and infrastructure.
What is Pfizer (PFE) free cash flow?: Pfizer (PFE) generated $9.08B in free cash flow for TTM through Q4 2025 (14.5% of total revenue). Free cash flow is the cash remaining after capital expenditures and represents the company's ability to fund growth, pay dividends, or reduce debt.

Data & methodology

What is a Sankey diagram?: A Sankey diagram shows how money flows through a company from revenue to net profit. The width of each flow represents its proportion.
How is the data calculated?: We use the income statement from company filings. For TTM (Trailing Twelve Months), we use a pre-aggregated twelve-month view aligned with our latest four quarterly periods. Revenue flows to cost of revenue and gross profit, then to operating expenses (R&D, S&M, G&A) and operating profit.
When was this data last updated?: Based on company filings through TTM through Q4 2025.