How does Illumina (ILMN) make money?

Illumina (ILMN) generates revenue primarily from Sequencing, which accounted for 91.8% of total revenue in TTM through Q1 2026. The company reported $4.39B in revenue and converted 19.4% of it into net profit, equivalent to roughly $853M in net income — what's left after the cost of revenue, operating expenses, interest, and income taxes.

What is the gross profit margin of Illumina (ILMN)?

Illumina (ILMN) reported a gross profit margin of 67.7% in TTM through Q1 2026, equivalent to $2.97B in gross profit on $4.39B in revenue. Gross margin measures how much of each dollar of revenue remains after the direct cost of producing or delivering the product — a higher figure typically signals pricing power, scale, or a less capital-intensive business model.

What is the operating profit margin of Illumina (ILMN)?

Illumina (ILMN) reported an operating profit margin of 21.5% in TTM through Q1 2026, equivalent to $942M in operating income. Operating margin captures profitability after research & development, sales & marketing, and general & administrative expenses — but before interest, taxes, and one-off items — and is the cleanest single read on the underlying business's efficiency.

What is the net profit margin of Illumina (ILMN)?

Illumina (ILMN) reported a net profit margin of 19.4% in TTM through Q1 2026, equivalent to $853M in net income. Net margin is the bottom-line share of revenue that survives every expense — operating costs, interest, and income taxes — and is the figure that flows directly into earnings per share.

Is Illumina (ILMN) profitable?

Yes. Illumina (ILMN) reported $853M in net income for TTM through Q1 2026, with a net profit margin of 19.4%. The company earned more from its operations than it paid out in costs, interest, and income taxes, leaving positive earnings on the bottom line.

How much does Illumina (ILMN) invest in research and development?

Illumina (ILMN) invested $949M in research and development during TTM through Q1 2026, roughly 21.6% of total revenue. R&D spending funds the company's future product pipeline and is expensed in full on the income statement rather than capitalised, which makes the operating margin sensitive to how aggressively management chooses to reinvest in innovation.

How much does Illumina (ILMN) spend on capital expenditures?

Illumina (ILMN) spent $139M on capital expenditures (CapEx) during TTM through Q1 2026, roughly 3.2% of total revenue. CapEx represents long-lived investment in property, equipment, data centres, and other physical infrastructure, and is subtracted from operating cash flow to arrive at free cash flow.

How much free cash flow does Illumina (ILMN) generate?

Illumina (ILMN) generated $989M in free cash flow during TTM through Q1 2026, a free-cash-flow margin of 22.5%. Free cash flow is the cash left after capital expenditures and represents the discretionary pool the company can use to pay dividends, repurchase shares, repay debt, or fund acquisitions without raising external capital.

What is the effective tax rate of Illumina (ILMN)?

Illumina (ILMN) had an effective tax rate of 19.6% in TTM through Q1 2026. The effective rate is the actual share of pre-tax income paid as income taxes and can differ materially from the statutory rate due to foreign earnings mix, tax credits (such as R&D), share-based compensation deductions, and one-off discrete items.

What are the main business segments of Illumina (ILMN)?

Illumina (ILMN) reports revenue across 2 reportable product segments, led by Sequencing at 91.8% of total revenue in TTM through Q1 2026. See the revenue-by-segment table on this page for the full breakdown and how each segment feeds into the income-statement waterfall above.

Where does Illumina (ILMN) generate most of its revenue?

Americas is the largest geographic market for Illumina (ILMN), accounting for 48.3% of revenue in the most recent annual filing. The complete regional split — including international markets and any Rest-of-World rollup — is shown in the revenue-by-geography table on this page.

How Illumina Makes Money: 2026 Visual Revenue Map

Illumina (ILMN) Income Statement Flow — TTM through Q1 2026

Calculated from the four most recent reported quarters, ending March 29, 2026 (reported May 4, 2026).

Illumina (ILMN) Revenue by Product Segment — TTM through Q1 2026

Aggregated from the four quarterly disclosures behind this TTM. Minor differences vs the company's annual filing can occur if reported segments changed mid-year.

Revenue contribution by product segment for Illumina (ILMN), TTM through Q1 2026.
Segment	Revenue (USD)	% of total
Sequencing	$4.03B	91.8%
Microarray	$360M	8.2%
Total	$4.39B	100%

Sequencing$4.03B
Microarray$360M
Total$4.39B

Illumina (ILMN) Revenue by Geography — TTM through Q1 2026

Aggregated from the four quarterly disclosures behind this TTM. Minor differences vs the company's annual filing can occur if reported regions changed mid-year.

Revenue contribution by geographic region for Illumina (ILMN), TTM through Q1 2026
Region	Revenue (USD)	% of total
Americas	$1.84B	48.3%
EMEA	$1.33B	34.9%
Asia Pacific	$417M	11%
CHINA	$223M	5.9%
Total	$3.8B	100%

Americas
EMEA
Asia Pacific
CHINA
Total

Revenue Breakdown — TTM through Q1 2026

In TTM through Q1 2026, Illumina (ILMN) reports revenue across 2 reportable product segments; the largest segment was Sequencing at 91.8%, followed by Microarray (8.2%). Geographically, Americas accounted for 48.3% of revenue, followed by EMEA (34.9%) and Asia Pacific (11%).

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