How does Illumina (ILMN) make money?

Illumina (ILMN) primarily makes money through Sequencing, which accounts for 91.8% of total revenue. For TTM through Q1 2026, Illumina generated $4.39B in total revenue with a net profit margin of 19.4%.

What is Illumina (ILMN) gross profit margin?

Illumina (ILMN) reported a gross profit margin of 67.7% for TTM through Q1 2026, equivalent to $2.97B in gross profit. This means Illumina retains 67.7% of each revenue unit after direct costs of production.

What is Illumina (ILMN) operating profit margin?

Illumina (ILMN) reported an operating profit margin of 21.5% for TTM through Q1 2026, equivalent to $942.00M in operating profit. This reflects profitability after operating expenses such as R&D, sales, and administration, but before taxes and non-operating items.

What is Illumina (ILMN) net profit margin?

Illumina (ILMN) reported a net profit margin of 19.4% for TTM through Q1 2026, equivalent to $853.00M in net profit. This is the share of revenue that remains as profit after all expenses, taxes, and non-operating items.

How much does Illumina (ILMN) invest in R&D?

Illumina (ILMN) invested $949.00M in research and development in TTM through Q1 2026 (21.6% of total revenue). R&D spending reflects investment in future products, services, and technologies.

How much does Illumina (ILMN) spend on capital expenditures?

Illumina (ILMN) spent $139.00M on capital expenditures in TTM through Q1 2026 (3.2% of total revenue). Capital expenditures represent investments in physical assets such as property, equipment, and infrastructure.

What is Illumina (ILMN) free cash flow?

Illumina (ILMN) generated $989.00M in free cash flow for TTM through Q1 2026 (22.5% of total revenue). Free cash flow is the cash remaining after capital expenditures and represents the company's ability to fund growth, pay dividends, or reduce debt.

What is Illumina (ILMN) effective tax rate?

Illumina (ILMN) had an effective tax rate of 19.6% for TTM through Q1 2026. This is the actual percentage of pre-tax income paid as income taxes.

What are Illumina (ILMN) main revenue segments?

Illumina (ILMN) reports revenue across 2 reportable product segments, led by Sequencing at 91.8% of total revenue in TTM through Q1 2026. The full segment-by-segment breakdown is shown in the revenue-by-segment table on this page.

Where does Illumina (ILMN) generate most of its revenue?

Geographically, 48.3% of Illumina (ILMN) revenue came from Americas in the most recent annual filing. The full regional split is shown in the revenue-by-geography table on this page.

How Illumina (ILMN) Makes Money: A Visual Guide

Illumina (ILMN) generated $4.39B in revenue, earning $853.00M in net profit (19.4% margin). Its largest revenue source is Sequencing (91.8% of revenue). Below is an interactive breakdown of how revenue flows through the income statement.

In TTM through Q1 2026, Illumina (ILMN) generated revenue across 2 reportable product segments; the largest contributor was Sequencing at 91.8%, followed by Microarray (8.2%). Geographically, Americas accounted for 48.3% of revenue, followed by EMEA (34.9%) and Asia Pacific (11%).

Illumina (ILMN) Income Statement Flow — TTM through Q1 2026

Calculated from the four most recent reported quarters, ending March 29, 2026 (reported February 12, 2026).

Illumina (ILMN) Revenue by Product Segment — TTM through Q1 2026

Sequencing
Revenue
$4.03B
% of total
91.8%
Microarray
Revenue
$359.84M
% of total
8.2%
Total
Revenue
$4.39B
% of total
100%

Segment	Revenue	% of total
Sequencing	$4.03B	91.8%
Microarray	$359.84M	8.2%
Total	$4.39B	100%

View Illumina (ILMN) revenue history

Illumina (ILMN) Revenue by Geography — TTM through Q1 2026

Aggregated across the four most recent quarters, matching the TTM through Q1 2026 income statement above. Region totals sum quarterly disclosures; minor differences vs the company's annual filing can occur if reported regions changed mid-year.

Americas
Revenue
$1.84B
% of total
48.3%
EMEA
Revenue
$1.33B
% of total
34.9%
Asia Pacific
Revenue
$417.00M
% of total
11%
CHINA
Revenue
$223.00M
% of total
5.9%
Total
Revenue
$3.80B
% of total
100%

Region	Revenue	% of total
Americas	$1.84B	48.3%
EMEA	$1.33B	34.9%
Asia Pacific	$417.00M	11%
CHINA	$223.00M	5.9%
Total	$3.80B	100%

View Illumina (ILMN) revenue history

Frequently asked questions

How does Illumina (ILMN) make money?: Illumina (ILMN) primarily makes money through Sequencing, which accounts for 91.8% of total revenue. For TTM through Q1 2026, Illumina generated $4.39B in total revenue with a net profit margin of 19.4%.
What is Illumina (ILMN) gross profit margin?: Illumina (ILMN) reported a gross profit margin of 67.7% for TTM through Q1 2026, equivalent to $2.97B in gross profit. This means Illumina retains 67.7% of each revenue unit after direct costs of production.
What is Illumina (ILMN) operating profit margin?: Illumina (ILMN) reported an operating profit margin of 21.5% for TTM through Q1 2026, equivalent to $942.00M in operating profit. This reflects profitability after operating expenses such as R&D, sales, and administration, but before taxes and non-operating items.
What is Illumina (ILMN) net profit margin?: Illumina (ILMN) reported a net profit margin of 19.4% for TTM through Q1 2026, equivalent to $853.00M in net profit. This is the share of revenue that remains as profit after all expenses, taxes, and non-operating items.
How much does Illumina (ILMN) invest in R&D?: Illumina (ILMN) invested $949.00M in research and development in TTM through Q1 2026 (21.6% of total revenue). R&D spending reflects investment in future products, services, and technologies.
How much does Illumina (ILMN) spend on capital expenditures?: Illumina (ILMN) spent $139.00M on capital expenditures in TTM through Q1 2026 (3.2% of total revenue). Capital expenditures represent investments in physical assets such as property, equipment, and infrastructure.
What is Illumina (ILMN) free cash flow?: Illumina (ILMN) generated $989.00M in free cash flow for TTM through Q1 2026 (22.5% of total revenue). Free cash flow is the cash remaining after capital expenditures and represents the company's ability to fund growth, pay dividends, or reduce debt.
What is Illumina (ILMN) effective tax rate?: Illumina (ILMN) had an effective tax rate of 19.6% for TTM through Q1 2026. This is the actual percentage of pre-tax income paid as income taxes.
What are Illumina (ILMN) main revenue segments?: Illumina (ILMN) reports revenue across 2 reportable product segments, led by Sequencing at 91.8% of total revenue in TTM through Q1 2026. The full segment-by-segment breakdown is shown in the revenue-by-segment table on this page.
Where does Illumina (ILMN) generate most of its revenue?: Geographically, 48.3% of Illumina (ILMN) revenue came from Americas in the most recent annual filing. The full regional split is shown in the revenue-by-geography table on this page.

Data & methodology

What is a Sankey diagram?: A Sankey diagram shows how money flows through a company from revenue to net profit. The width of each flow represents its proportion.
How is the data calculated?: We use the income statement from company filings. For TTM (Trailing Twelve Months), we use a pre-aggregated twelve-month view aligned with our latest four quarterly periods. Revenue flows to cost of revenue and gross profit, then to operating expenses (R&D, S&M, G&A) and operating profit.
Where do segment and geographic numbers come from?: Product-segment shares come from the same TTM income statement that powers the Sankey chart. Geographic splits are first rebuilt from the four most recent quarterly geographic-segmentation filings so they align with the same TTM window; if quarterly geo data is missing, we fall back to the latest annual disclosure (the table heading shows which one is in use).
When was this data last updated?: Based on company filings through TTM through Q1 2026.